Table 2 Characteristics of the risk studies

Author

Country

Study design

Study population

Sample size

Age (years)

C. H. Chang et al. [30] (2017)

China

Retrospective cohort study

NHIRD

6237

9.7 ± 4.2

M. M. Perfect et al. [23] (2013)

United States

Prospective cohort study

TuCASA

152

13.25 ± 1.71

Author

Primary outcomes

The proportion of neurobehavioral deficits

Covariates

Observational period (years)

NOS scale (max 9)

C. H. Chang et al. [30] (2017)

One or more depressive disorders

SDB group: 14/567 (2.47%) Control group: 63/5670 (1.11%)

Age, sex, hypertension, diabetes, insomnia, ADHD, obesity, asthma, Charlson comorbidity score

5.87

8

M. M. Perfect et al. [23] (2013)

Behavioral impairment

SDB group: 6/17 (35.29%) Control group: 10/135 (7.41%)

Sex

5

7