Table 5 Linear regression analysis for association of insulin resistance indices in 2 genotype groups in 3 models. P values less than 0.05 are shown in bold

HOMA-IR

Data

Model 1

Model 2

Model 3

OR (CI 95%)

p value

OR (CI 95%)

p value

OR (CI 95%)

p value

BsmI (rs1544410)

Dominant (BB + Bb) Vs bb

-0.033 (-0.228, 0.136)

0.620

-0.026 (-0.212, 0.141)

0.694

-0.036 (-0.226, 0.127)

0.581

Recessive (Bb + bb) Vs BB

-0.111 (-0.420, 0.035)

0.097

-0.116 (-0.421, 0.020)

0.074

-0.129 (-0.448, -0.004)

0.046

FIRI

Model 1

Model 2

Model 3

OR (CI 95%)

p value

OR (CI 95%)

p value

OR (CI 95%)

p value

Dominant (BB + Bb) Vs bb

0.001 (-0.151, 0.153)

0.992

0.009 (-0.136, 0.158)

0.884

-0.006 (-0.154, 0.139)

0.921

Recessive (Bb + bb) Vs BB

-0.125 (-0.378, -0.002)

0.048

-0.132 (-0.383, -0.018)

0.031

-0.148 (-0.409, -0.045)

0.015

Insulin-to-glucose ratio

Model 1

Model 2

Model 3

OR (CI 95%)

p value

OR (CI 95%)

p value

OR (CI 95%)

p value

Dominant (BB + Bb) Vs bb

-0.023 (-0.343, 0.235)

0.713

-0.019 (-0.333, 0.243)

0.756

-0.041 (-0.380, 0.185)

0.497

Recessive (Bb + bb) Vs BB

-0.134 (-0.377, -0.019)

0.031

-0.137 (-0.381, -0.024)

0.026

-0.153 (-0.404, -0.053)

0.011

QUICKI

Model 1

Model 2

Model 3

OR (CI 95%)

p value

OR (CI 95%)

p value

OR (CI 95%)

p value

Dominant (BB + Bb) Vs bb

0.021 (-0.005, 0.007)

0.746

0.015 (-0.005, 0.006)

0.813

0.028 (-0.004, 0.007)

0.661

Recessive (Bb + bb) Vs BB

0.096 (-0.002, 0.012)

0.135

0.100 (-0.001, 0.013)

0.111

0.113 (-0.001, 0.013)

0.071

Bennett’s index

Model 1

Model 2

Model 3

OR (CI 95%)

p value

OR (CI 95%)

p value

OR (CI 95%)

p value

Dominant (BB + Bb) Vs bb

0.066 (-0.103, 0.341)

0.293

0.068 (-0.101, 0.344)

0.283

0.073 (-0.093, 0.356)

0.251

Recessive (Bb + bb) Vs BB

0.036 (-0.199, 0.359)

0.573

0.034 (-0.202, 0.356)

0.585

0.037 (-0.199 ,0.366)

0.561

McAuley

Model 1

Model 2

Model 3

OR (CI 95%)

p value

OR (CI 95%)

p value

OR (CI 95%)

p value

Dominant (BB + Bb) Vs bb

0.095 (-0.025, 0.181)

0.136

0.093 (-0.026, 0.179)

0.145

0.114 (-0.008, 0.194)

0.070

Recessive (Bb + bb) Vs BB

0.041 (-0.087, 0.171)

0.525

0.043 (-0.086, 0.173)

0.506

0.051 (-0.075, 0.181)

0.414

Revised McAuley

Model 1

Model 2

Model 3

OR (CI 95%)

p value

OR (CI 95%)

p value

OR (CI 95%)

p value

Dominant (BB + Bb) Vs bb

0.085 (-0.037, 0.196)

0.179

0.083 (-0.039, 0.194)

0.189

0.111 (-0.007, 0.214)

0.067

Recessive (Bb + bb) Vs BB

0.030 (-0.112, 0.183)

0.634

0.033 (-0.109, 0.186)

0.608

0.051 (-0.081, 0.200)

0.403