Short term effect of intravenous treprostinil in term and preterm infants with pulmonary hypertension

BMC Pediatrics

Table 4 Characteristics of responders and non-responders to treprostinil in echocardiography among preterm infants

	GA (weeks)	Birthweight (gm)	Sex	Associated conditions	Treprostinil (PND)	Conditions at treprostinil start					Outcomes
	GA (weeks)	Birthweight (gm)	Sex	Associated conditions	Treprostinil (PND)	Weight (g)	Mode of ventilator	RSS	Inhaled NO (ppm)	At 4 weeks	At discharge
Non-responder	34.7	2,540	Male	CDH	1	2,540	HFOV	9.8	70	Died
	34	2,050	Male	CDH	7	2,430	HFOV	8	80	Died
	31.1	1,210	Male	Down syndrome	73	2,620	HFOV	11	80	Died
	23.6	660	Male	PPHN	11	920	HFOV	12.4	40	Died
	27.4	1,140	Male	PPHN	4	1,440	HFOV	8.4	50	Survived	Survived
	34.7	2,600	Female	PPHN	14	2,650	HFOV	13.6	80	Died
	33.1	2,010	Male	PPHN, Potter sequence	1	2,010	HFOV	11.2	60	Died
	28.4	390	Female	Severe BPD	314	7,350	HFOV	8.4	20	Survived	Survived
	26.9	830	Female	Severe BPD	298	4,920	Conventional	13.6	11	Survived	Survived
	24.9	770	Female	Severe BPD	39	1,460	HFOV	16	40	Survived	Survived
	24.4	710	Male	Severe BPD	18	700	Conventional	12.4	80	Died
Responder	35.7	2,340	Male	CDH	10	2,900	HFOV	8.4	40	Survived	Died
	30.6	600	Male	PPHN, Severe BPD	4	530	HFOV	6.2	40	Survived	Survived
	24.9	700	Male	Severe BPD	19	850	Conventional	6	30	Survived	Died
	24.4	690	Female	Severe BPD	32	890	HFOV	6.6	60	Survived	Survived
	33.4	2,490	Female	Severe BPD	121	5,110	Conventional	12.9	60	Survived	Survived
	30.9	740	Male	Severe BPD,	45	1,340	Conventional	18	40	Survived	Died
	31.9	790	Male	EA, severe BPD, chylothorax	54	1,750	Conventional	16.1	80	Survived	Died

GA, gestational age; PND, postnatal days; CDH, congenital diaphragmatic hernia; PPHN, persistent pulmonary hypertension; BPD, bronchopulmonary dysplasia; HFOV, high frequency oscillatory ventilation; EA, esophageal atresia

ISSN: 1471-2431