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Table 1 Demographic, clinical and EEG characteristics

From: Clinical manifestations and EEG findings in children infected with COVID-19 and exhibiting neurological symptoms

Variable

Gender

Male

  

77

(61.60%)

 

Female

  

48

(38.40%)

 

Age (Mean ± SD, year)

   

5.24 ± 3.44 ( overall range: 0.1–14.6)

 

Fever

No

  

21

(16.80%)

 

Yes

  

104

(83.20%)

 

Consciousness

Normal

  

116

(92.80%)

 

Abnormal

  

9

(7.20%)

 

Glasgow Coma Scale score

   

10.5

(7.25,14.5)

N = 4

Brain image

Normal

  

40

(78.43%)

N = 51

Abnormal

  

11

(21.57%)

N = 51

Diagnosis

Epilepsy

  

23a

(18.40%)

 

Febrile seizures

 

51

(40.80%)

 

Complex febrile seizures

 

29

(23.20%)

 

Febrile seizures plus

 

4

(3.20%)

 

Epileptic seizures

 

7

(5.60%)

 

Encephalitisb/encephalopathy

4

(3.20%)

 

Others

  

7

(5.60%)

 

Clinical seizure

None

  

3

(2.40%)

 

Once

  

81

(64.80%)

 

Twice

  

19

(15.20%)

 

More than twice

 

22

(17.60%)

 

Form of seizure

Generalized clinical

 

112

(91.80%)

N = 122

Focal clinical

 

10

(8.20%)

N = 122

Presence of status epilepticus

   

6

(4.80%)

 

Seizure frequency compared to previous

No prior seizures

 

66

(52.80%)

 

Increase

  

16

(12.80%)

 

Same as before

 

25

(20.00%)

 

Decrease

  

0

(0.00%)

 

Unknown

  

18

(14.40%)

 

History of neurological illness

None

  

68

(54.40%)

 

Febrile seizures

 

35

(28.00%)

 

Epilepsy

  

15

(12.00%)

 

Others

  

7

(5.60%)

 

Prior family history of seizures

None

  

115

(92.00%)

 

Yes

  

10

(8.00%)

 

Antiseizure medicine before EEG

None

  

100

(80.00%)

 

Yes

  

25

(20.00%)

 

Interval time between EEG and last seizure (median [IQR], day)

   

3

(1,8)

 

Hospitalization

None

  

98

(78.40%)

 

Yes

  

27

(21.60%)

 

Department

Outpatient

  

98

(78.40%)

 

Neurology department

 

15

(12.00%)

 

ICU

  

4

(3.20%)

 

Infection department

 

1

(0.80%)

 

Transition ward

 

3

(2.40%)

 

Other departments

 

4

(3.20%)

 

Total length of stay (median [IQR], day)

   

7

(5,11)

 

Outcome at discharge

Recovery

  

122

(97.60%)

 

Neurological sequalae

 

3

(2.40%)

 

EEG

Normal

  

86

(68.80%)

 

Abnormal

  

39

(31.20%)

 
 

Background abnormalities

16

(41.03%)

N = 39

 

Background slowing

11

(28.21%)

N = 39

 

Focal slowing

5

(12.82%)

N = 39

 

Abnormal discharges

17

(43.59%)

N = 39

 

Background abnormalities + abnormal discharges

6

(15.38%)

N = 39

  1. Abbreviations: SD standard deviation, IQR Interquartile range, ICU intensive care unit
  2. a. Seven of the 23 patients were first diagnosed with epilepsy during our study period
  3. b. The criteria of encephalitis were used as described in the Consensus Statement of the International Encephalitis Consortium [12]