Table 1 Clinical characteristics of 26 patients

Sex, no./total (%)

 Male

16 (61.5%)

 Female

10 (38.5%)

Age at diagnosis, [years, median (range)]

5.87 (0.25−13)

Diagnosis, no./total (%)

 RCC

16 (61.5%)

 Advanced MDS

10 (38.5%)

Hematological characteristics

 Cytopenia, 1 lineage,no./total (%)

3 (11.5%)

 Cytopenias, 2 lineages, no./total (%)

10 (38.5%)

 Pancytopenia, no./total (%)

13 (50%)

 Hb level,median (range), < 100 g/l

78 (44–125)

 PLT count,median (range), < 100 × 10⁹/L

54 (10–263)

 NE count, median (range), < 1.5 × 10⁹/L

1.41 (0.13–5.08)

Abnormal karyotype, no./total (%)

9 (34.6%)

 Monosomy 7

5 (19.2)

 Complex karyotype

1 (3.9%)

 Other

3 (11.5%)

Gene mutation

13(50%)