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Table 2 Demographic, clinical, and laboratory findings for comparison of case and control group

From: Tic disorder in allergic rhinitis children and adolescents: a case-control study

Variable

Case Group

(Accompanying allergic rhinitis and tic)

N = 47

Control Group

(Allergic rhinitis alone)

N = 47

P.value*

Age, Mean ± SD

10.46 ± 3.97

9.27 ± 3.18

0.112

Age of allergic rhinitis, Mean ± SD

7.63 ± 3.90

6.41 ± 4.12

0.143

Age of asthma onset (year), Mean ± SD

7.69 ± 3.44

4.75 ± 2.86

≤ 0.001

Sex, N (%)

Female

22(46.8)

19(40.42)

0.532

Male

25(53.2)

28(59.58)

The first child of the family, N (%)

28(59.6)

30(63.83)

0.671

Family history of allergies, N (%)

24(51.1)

26(55.33)

0.679

Antibiotic use in early life, N (%)

27(57.4)

25(53.20)

0.678

The history of passive exposure of the mother to cigarette smoke in the first year of life, N (%)

6(12.8)

8(17.03)

0.562

Mother’s smoking during pregnancy, N (%)

1(2.1)

2(4.26)

0.557

Preterm birth, N (%)

5(10.6)

8(17.03)

0.370

Day of the week AR symptoms, N (%)

3 days a week

3(6.4)

20(42.55)

≤ 0.001

4 days a week

1(2.1)

1(2.1)

Every day

43(91.5)

26(55.35)

Sleep disturbance due to AR, N (%)

18(38.3)

17(36.18)

0.831

Disruption at work or school due to AR, N (%)

13(27.7)

8(17.03)

0.215

History of infantile eczema, N (%)

10(21.3)

8(17.03)

0.600

Associated with asthma, N (%)

15(31.9)

27(57.45)

0.012

Seasonal exacerbation of AR, N (%)

24(51.1)

32(68.09)

0.092

Frequent colds, N (%)

19(40.4)

8(17.03)

0.012

Night cough in colds, N (%)

24(51.1)

15(31.92)

0.059

Active cough in colds, N (%)

28(59.6)

27(57.45)

0.834

Active cough without a cold, N (%)

18(38.3)

13(27.66)

0.272

Food allergy in infancy, N (%)

5(10.6)

9(19.15)

0.246

Taking medication for AR, N (%)

44(93.6)

35(74.47)

0.0113

Improvement of AR symptoms with medication, N (%)

41(93.2)

45(95.74)

0.591

History of sinusitis, N (%)

6(12.8)

12(25.54)

0.115

History of conjunctivitis, N (%)

7(14.9)

8(17.03)

0.778

History of middle ear infection, N (%)

13(27.7)

20(42.56)

0.130

History of other mental and neurological diseases, N (%)

2(4.3)

1(2.13)

0.557

Drug history, N (%)

3(6.4)

2(4.26)

0.645

  1. SD: Standard Deviation
  2. IQR: interquartile range
  3. AR: rheumatoid arthritis
  4. * Comparison of case and control group, Use of Independent t test(parametric) or Mann–Whitney U test(non-parametric) OR Chi square test