Table 3 Mean number of stools and percent of painful defecation among participants at baseline and after 3 months
Variable | Baseline | 2 Months | 3 Months | |||||
|---|---|---|---|---|---|---|---|---|
Placebo (n = 67) | Risperidone (n = 69) | Placebo (n = 67) | Risperidone (n = 69) | Placebo (n = 67) | Risperidone (n = 69) | P value | P value | |
Number of nocturnal stools | 0.20(0.95) | 0.33(0.65) | 0.03(0.21) | 0.24(0.58) | 0.03(0.17) | 0.05(0.22) | 0.44b | |
With psychiatric disorder | 0.41(1.50) | 0.32(0.47) | 0.09(0.29) | 0.24(0.52) | 0.05(0.21) | 0.08(0.27) | 0.39a | |
No psychiatric disorder | 0.0(0.0) | 0.33(0.73) | 0.0(0.0) | 0.24(0.70) | 0.0(0.0) | 0.0(0.0) | ||
Number of diurnal stools1 | 5.28(2.73) | 6.28(2.79) | 4.33(3.35) | 3.03(2.92) | 1.92(1.81) | 1.31(1.83) | < 0.001b | |
With psychiatric disorder | 8.24(3.53) | 7.01(2.34) | 5.42(3.82) | 3.75(3.33) | 1.80(1.43) | 1.50(1.88) | 0.48a | |
No psychiatric disorder | 2.31(1.93) | 5.55(3.59) | 3.23(2.80) | 2.31(2.51) | 2.05(2.19) | 1.13(1.78) | ||
Painful defecation2 | 36(53.7) | 46(66.6) | 32(47.7) | 35(50.7) | 7(10.4) | 9(13.0) | 0.49c | |
With psychiatric disorder | 20(29.8) | 24(34.7) | 10(14.9) | 16(23.18) | 4(5.9) | 5(7.2) | 0.49 c | |
No psychiatric disorder | 16(23.8) | 22(31.8) | 22(32.8) | 19(27.5) | 3(4.4) | 4(5.7) | 0.47 c | |