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Table 2 8–10 year child weight, anthropometric, blood pressure and pulse wave velocity outcomes by treatment group

From: Effects of an antenatal dietary intervention in women with obesity or overweight on child outcomes at 8–10 years of age: LIMIT randomised trial follow-up

Outcome

Lifestyle Advice

n = 1065

Standard Care

n = 1056

Unadjusted Estimate (95% CI)

Unadjusted p value

Adjusted Estimate (95% CI)

Adjusted p value

BMI z-score > 85th Percentile#

479 (45.02)

507 (47.75)

0.94 (0.83, 1.07)

0.379

0.93 (0.82, 1.06)

0.302

Weight (kg)a

36.69 (35.87, 37.51)

36.51

(35.74, 37.28)

0.18 (-0.93, 1.30)

0.747

0.05 (-1.02, 1.11)

0.934

Weight z-score

1.02

(0.90, 1.13)

1.00

(0.89, 1.11)

0.02 (-0.14, 0.17)

0.835

0.00 (-0.15, 0.16)

0.984

Height (cm)a

137.80 (137.21, 138.39)

137.97 (137.42, 138.52)

-0.17 (-0.97, 0.64)

0.688

-0.17 (-0.90, 0.56)

0.642

Height z-score

0.53

(0.45, 0.60)

0.54

(0.46, 0.62)

-0.01 (-0.12, 0.09)

0.801

-0.01 (-0.12, 0.09)

0.793

BMI (kg/m2)a

19.04

(18.71, 19.37)

18.88 (18.60, 19.16)

0.16 (-0.28, 0.61)

0.476

0.10 (-0.33, 0.53)

0.651

BMI z-score

0.98

(0.87, 1.09)

0.94

(0.83, 1.05)

0.04 (-0.11, 0.19)

0.603

0.02 (-0.13, 0.17)

0.773

Head Circumference (cm)a

53.54

(53.39, 53.69)

53.60

(53.45, 53.74)

-0.06 (-0.26, 0.15)

0.598

-0.05 (-0.25, 0.15)

0.610

Abdomen Circumference (cm)a

66.27 (65.40, 67.15)

65.66

(64.75, 66.57)

0.61 (-0.62, 1.85)

0.332

0.45 (-0.75, 1.66)

0.461

Arm Circumference (cm)a

22.62

(22.30, 22.94)

22.37

(22.08, 22.66)

0.25 (-0.17, 0.67)

0.245

0.19 (-0.21, 0.60)

0.351

Weight z-score > 85th Percentile+

505 (47.40)

528 (50.03)

0.95 (0.83, 1.08)

0.414

0.94 (0.83, 1.07)

0.354

Weight z-score > 90th Percentile#

426 (39.96)

437 (41.42)

0.96 (0.84, 1.11)

0.627

0.95 (0.83, 1.10)

0.527

BMI z-score > 90th Percentile#†

415 (39.00)

431 (40.8)

0.96 (0.83, 1.11)

0.553

0.95 (0.82, 1.09)

0.446

Biceps SFTM (mm)a

10.54

(9.99, 11.09)

10.14

(9.63, 10.65)

0.39 (-0.36, 1.15)

0.306

0.29 (-0.44, 1.03)

0.432

Triceps SFTM (mm)a

15.62

(14.91, 16.32)

15.71

(15.12, 16.30)

-0.09 (-0.98, 0.80)

0.837

-0.19 (-1.07, 0.68)

0.666

Subscapular SFTM (mm)a

11.25

(10.52, 11.98)

10.89

(10.25, 11.52)

0.36 (-0.59, 1.32)

0.456

0.23 (-0.70, 1.16)

0.623

Supra SFTM (mm)a

15.74

(14.66, 16.83)

15.43

(14.41, 16.44)

0.32 (-1.15, 1.79)

0.672

0.15 (-1.30, 1.61)

0.835

Abdomen SFTM (mm)a

17.90

(16.80, 18.99)

17.17

(16.13, 18.22)

0.73 (-0.72, 2.17)

0.325

0.55 (-0.88, 1.98)

0.453

Thigh SFTM (mm)a

25.63

(24.37, 26.90)

25.32

(24.24, 26.40)

0.31 (-1.33, 1.95)

0.711

0.14 (-1.46, 1.74)

0.867

Sum of SFTM (mm)a

95.78

(90.03, 101.52)

91.73

(87.41, 96.06)

4.05 (-3.07, 11.16)

0.265

3.26 (-3.72, 10.24)

0.360

Fat Free Mass (kg)

25.78

(25.24, 26.31)

26.19

(25.69, 26.69)

-0.41 (-1.15, 0.32)

0.270

-0.47 (-1.20, 0.27)

0.215

Total Fat Mass (kg)

10.68

(9.95, 11.40)

10.62

(9.82, 11.42)

0.06 (-0.94, 1.05)

0.907

-0.00 (-0.99, 0.99)

0.996

Percentage Fat Mass (kg)

27.76

(26.49, 29.03)

27.28

(26.11, 28.45)

0.48 (-1.27, 2.22)

0.592

0.41 (-1.33, 2.15)

0.646

Systolic Blood Pressure (mmHg)a

108.31

(107.52, 109.10)

108.18

(107.34, 109.02)

0.13 (-0.99, 1.24)

0.823

0.08 (-1.03, 1.19)

0.884

Diastolic Blood Pressure (mmHg)a

67.18

(66.44, 67.91)

66.93

(66.13, 67.73)

0.24 (-0.82, 1.31)

0.655

0.26 (-0.81, 1.33)

0.634

Pulse Wave Velocity (m/s)b

4.60

(4.46, 4.74)

4.41

(4.30, 4.52)

0.19 (0.01, 0.37)

0.037

0.20 (0.02, 0.37)

0.029

  1. Outcomes are continuous unless otherwise indicated. Descriptives are mean (SD) and estimates are differences in means (Lifestyle Advice – Standard Care) and 95% Confidence Interval from linear regression models
  2. Outcomes marked ‘#’ are binary; descriptives are N (%), with frequencies calculated from estimated proportions combined across imputations. Estimates are Relative Risks and 95% Confidence Interval from log binomial regression models
  3. † Log Poisson regression with robust variance estimation used for adjusted model due to convergence issues with log binomial
  4. Adjusted estimates are from models adjusted for study centre, parity, maternal BMI category, smoking status, maternal age at trial entry and SEIFA Index of Relative Socio-economic Disadvantage (IRSD) quintile
  5. a = adjusted for child sex and actual age at assessment
  6. b = Sensitivity analysis for this outcome was conducted in which three outlier observations (all in Lifestyle Advice Group) were removed; adjusted estimate for this analysis was 0.11 (-0.02, 0.24), p = 0.087