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Table 1 Characteristics of patients

From: Treatment of children with refractory/relapse high risk langerhans cell histiocytosis with the combination of cytarabine, vindesine and prednisone

Parameters

The LAC group

n = 13

The HAC group

n = 7

General

  

Gender (male), n(%)

5 (38.46%)

6 (85.71%)

Median Age (year), (range)

1.67 (0.33–4.58)

2.67 (1.42–9.83)

DAS after initial therapy

2 (0–5)

2 (0–7)

Duration before diagnosis (W)

44.71 (6.14−120.43)

20.14 (8−156.43)

Follow-up time (years)

4.10 (0.92–6.67)

5.21 (2.68–6.23)

Organ involvement and Laboratory tests

  

Liver involvement

11 (84.61%)

6 (85.761%)

Spleen involvement

7 (53.85%)

3 (42.86%)

Hematology dysfunction

3 (23.08%)

0 (0%)

AST (U/L)

34.3 (11.3-131.6)

53.8 (17.9–98.8)

ALT (U/L)

16.9 (9.2-226.3)

30.6 (10.1–82.5)

γ-GGT (U/L)

24 (12.2−182.1)

33.7 (9.1−479.7)

  1. LAC, low-dose Ara-c chemotherapy; HAC, high-dose Ara-c chemotherapy; DAS, disease activity score; ALT, alanine aminotransferase; AST, aspartate aminotransferase; r-GGT, gamma glutamyltranspeptidase