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Table 1 Clinical characteristics of participants

From: Basal gonadotropin levels combine with pelvic ultrasound and pituitary volume: a machine learning diagnostic model of idiopathic central precocious puberty

Variables

ICPP group (nā€‰=ā€‰263)

non-CPP group (nā€‰=ā€‰192)

P value

Age, years

8.15ā€‰Ā±ā€‰1.17

8.21ā€‰Ā±ā€‰1.20

0.259

BA-CA, years

1.89ā€‰Ā±ā€‰1.62

1.40ā€‰Ā±ā€‰1.03

0.243

Weight, kg

29.64ā€‰Ā±ā€‰5.74

28.41ā€‰Ā±ā€‰5.59

0.023

Height, cm

130.24ā€‰Ā±ā€‰7.79

132.09ā€‰Ā±ā€‰7.28

0.010

BMI, kg/m2

16.86ā€‰Ā±ā€‰2.09

16.62ā€‰Ā±ā€‰1.95

0.204

Tanner stage (breast)

2.56ā€‰Ā±ā€‰0.71

2.19ā€‰Ā±ā€‰0.56

<ā€‰0.001

Tanner stage (pubic hair)

1.29ā€‰Ā±ā€‰0.44

1.15ā€‰Ā±ā€‰0.43

0.824

Baseline LH, IU/L

1.04ā€‰Ā±ā€‰1.54

0.34ā€‰Ā±ā€‰0.64

<ā€‰0.001

Baseline FSH, IU/L

3.86ā€‰Ā±ā€‰2.48

2.86ā€‰Ā±ā€‰1.76

<ā€‰0.001

Baseline LH/FSH ratio

0.39ā€‰Ā±ā€‰1.42

0.10ā€‰Ā±ā€‰0.12

0.001

Baseline Estradiol, pg/mL

28.61ā€‰Ā±ā€‰17.80

24.84ā€‰Ā±ā€‰13.70

0.011

PRL, ng/mL

11.10ā€‰Ā±ā€‰5.74

10.83ā€‰Ā±ā€‰6.02

0.618

Pituitary

Ā Ā Ā 

Height, mm

5.18ā€‰Ā±ā€‰1.11

4.93ā€‰Ā±ā€‰1.16

0.080

Volume, mm3

356.52ā€‰Ā±ā€‰113.41

343.92ā€‰Ā±ā€‰85.28

0.178

Shape grade

2.02ā€‰Ā±ā€‰0.60

1.96ā€‰Ā±ā€‰0.58

0.256

Uterine

Ā Ā Ā 

Length, mm

22.50ā€‰Ā±ā€‰5.51

19.85ā€‰Ā±ā€‰4.35

<ā€‰0.001

Anteroposterior diameter, mm

14.88ā€‰Ā±ā€‰5.55

13.20ā€‰Ā±ā€‰4.95

<ā€‰0.001

Transverse diameter, mm

11.06ā€‰Ā±ā€‰4.60

8.81ā€‰Ā±ā€‰3.39

<ā€‰0.001

Uterus volume, mL

2.45ā€‰Ā±ā€‰2.95

1.48ā€‰Ā±ā€‰1.64

<ā€‰0.001

Cervical

Ā Ā Ā 

Anteroposterior diameter, mm

11.09ā€‰Ā±ā€‰3.25

10.57ā€‰Ā±ā€‰3.04

0.085

FCR

1.34ā€‰Ā±ā€‰0.23

1.24ā€‰Ā±ā€‰0.23

<ā€‰0.001

Presence of endometrium, n (%)

180 (68.44)

101 (52.60)

<ā€‰0.001

Ovary

Ā Ā Ā 

Length, mm

24.87ā€‰Ā±ā€‰4.33

23.91ā€‰Ā±ā€‰3.38

0.215

Width, mm

12.01ā€‰Ā±ā€‰2.75

11.50ā€‰Ā±ā€‰2.31

0.286

Height, mm

14.09ā€‰Ā±ā€‰3.32

14.37ā€‰Ā±ā€‰4.21

0.653

Average volume, mL

2.31ā€‰Ā±ā€‰1.09

2.03ā€‰Ā±ā€‰0.94

0.004

  1. ICPP: idiopathic central precocious puberty; LH: Luteinizing hormone; FSH: Follicular-stimulating hormone; PRL: prolactin; BA, bone age; CA, chronological age; BMI, body mass index; FCR, Ratio of fundus to cervix