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Table 2 Clinical characteristics of patients after treatment

From: Effects of different therapy regimens to increase final adult height in males at advanced bone age with idiopathic short stature

Clinical characteristics

rhGH

n = 22

GnRHa + GH

n = 22

AI + GH

n = 24

P

Age* (years)

15.1 ± 1.12a

16.1 ± 0.94ac

14.8 ± 1.10c

 < 0.05

Bone age*(years)

15.2 ± 0.53ab

14.1 ± 0.47a

14.3 ± 0.45b

 < 0.05

HtSDS-CA*

0.12 ± 0.65

0.03 ± 0.34c

0.39 ± 0.47c

 < 0.05

HtSDS-BA*

-0.14 ± 0.18ab

0.60 ± 0.29a

0.51 ± 0.24b

 < 0.05

Duration (months)

24.9 ± 4.47a

34.1 ± 3.36ac

22.7 ± 2.49c

 < 0.05

Height*(cm)

169.8 ± 0.83

171.2 ± 0.81

170.6 ± 0.75

 > 0.05

AHt

170.9 ± 0.7ab

173.5 ± 1.0a

173.2 ± 1.5b

 < 0.05

AHtSDS

-0.29 ± 0.1ab

0.07 ± 0.2a

0.09 ± 0.2b

 < 0.05

IGF-1* (nmol/L)

62.1 ± 19.6b

74.6 ± 23.4

80.9 ± 20.8b

 < 0.05

TSH* (mIu/L)

1.92 ± 0.96

1.65 ± 0.57

1.69 ± 0.77

 > 0.05

T4* (Pmol/L)

15.9 ± 2.2

14.5 ± 3.1

15.7 ± 3.2

 > 0.05

  1. *: when therapy discontinued. HtSDS-CA: the standard deviation score of chronological age and height, HtSDS-BA:the standard deviation score of bone age and height, AHt: Adult Height, AHtSDS: AHt standard deviation score
  2. aP < 0.05(Comparison between GH group and GnRHa + GH group),bP < 0.05(Comparison between GH group and AI + GH group), cP < 0.05(Comparison between GnRHa + GH group and AI + GH group)