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Table 1 Baseline characteristics in the survival and death groups of patients with PH.

From: Echocardiographic measurements of left ventricular dimensions and function in newborns with omphalocele and pulmonary

 

Survived

(n = 14)

Did not survive

(n = 4)

P-value

Patient information

   

 Gender (male)

8 (57.1%)

2 (50.0%)

1.000

 GA (weeks), median (IQR)

38.0 (37.5–38.9)

36.3 (32.4–38.7)

0.420

 Preterm (< 37 weeks GA)

3 (21.4%)

2 (50.0%)

0.533

 BW (kg), median (IQR)

3.0 (2.5–3.4)

2.4 (1.5–2.9)

0.089

 Low BW (< 1500 g)

3 (21.4%)

2 (50.0%)

0.533

 BL (cm), median (IQR)

48.5 (46.8–50.0)

44.0 (40.8–48.8)

0.146

 BH (cm), median (IQR)

34.0 (32.5–35.0)

32.5 (28.4–34.0)

0.186

 BC (cm), median (IQR)

32.0 (30.0-33.3)

28.5 (25.5–31.5)

0.097

 1-min Apgar

8.0 (7.0–10.0)

7.5 (5.3–9.8)

0.440

 Low Apgar score (< 7)

2 (14.3%)

2 (50.0%)

0.197

 5-min Apgar

10.0 (9.8–10.0)

9.5 (8.25-10.0)

0.311

 Intubation at birth

1 (7.1%)

2 (50.0%)

0.108

 GO

11 (78.6%)

4 (100%)

-

 Content of omphalocele

   

 Liver

11 (78.6%)

4 (100%)

-

 Stomach

5 (35.7%)

3 (75.0%)

0.275

 Spleen

3 (21.4%)

2 (50.0%)

0.533

 Stage closure

9 (64.3%)

4 (100%)

-

Maternal Information

   

 Maternal age (years)

30.0 (27.5–36.3)

29.5 (26.5–31.8)

0.749

 Adverse pregnancy

1.0 (0–2.0)

1.5 (1.0-2.8)

0.379

 Pregnancy-induced hypertension

1 (7.1%)

1 (25.0%)

0.405

 Gestational diabetes

2 (14.3%)

2 (50.0%)

0.197

 Medication use in pregnancy

9 (64.3%)

2 (50.0%)

1.000

PH

   

 Age at diagnosis (days)

3.5 (2.8–9.5)

2.5 (2.0-4.5)

0.232

Pulmonary vasodilator therapy

   

 Age at therapy (days)

7.5 (4.8–19.0)

5.5 (3.3–9.3)

0.394

 Nitric oxide

2 (14.3%)

1 (25%)

1.000

 Sildenafil

13 (92.9%)

4 (100%)

-

 Bosentan

7 (50%)

0

-

  1. GA: gestational age; BW: birth weight; BL: birth length; BH: birth head circumference; BC: birth chest circumference; GO: giant omphalocele; IQR: interquartile range; PH: pulmonary hypertension