Table 1 Outcome Measures
Type | Outcome | Method | Year 1 | Year 2 | Year 3 | Year 4 | Year 5 | Recording | Analysis |
|---|---|---|---|---|---|---|---|---|---|
Primary | FEV1 | Annual health assessment: spirometry | school visit | school visit | school visit | school visit | school visit | Spirometer download | Interaction analysis |
Exposures | Air quality: NO, NO2, PM10, PM2.5 | k-means clustering developed by Font et al.(27) | LAQN* and AURN** | LAQN and AURN | LAQN and AURN | LAQN and AURN | LAQN and AURN | LAQN and AURN | Interaction analysis |
Secondary | FVC and other spirometric variables | Annual health assessment: spirometry | school visit | school visit | school visit | school visit | school visit | Spirometer download | Interaction analysis |
Secondary | Physical activity and GPS tracking | Annual health assessment: accelerometer and GPS tracker | school visit | school visit | school visit | school visit | school visit | Accelerometer and GPS download | Interaction analysis |
Demography / potential confounding variables | Parent-completed questionnaire: (paper or web) | school bag prior to school visit | school bag prior to school visit | school bag prior to school visit | school bag prior to school visit | school bag prior to school visit | Clinical Record Form | Interaction analysis | |
Secondary | School absence; work absence | Parent-completed questionnaire: (paper or web) | school bag prior to school visit | school bag prior to school visit | school bag prior to school visit | school bag prior to school visit | school bag prior to school visit | Clinical Record Form | Interaction analysis |
Secondary | Respiratory and allergy symptoms (ISAAC+) | Parent-completed questionnaire: (paper or web) | school bag prior to school visit | school bag prior to school visit | school bag prior to school visit | school bag prior to school visit | school bag prior to school visit | Clinical Record Form | Interaction analysis |
Secondary | QOL (CHU9D++) | Parent-completed questionnaire: (paper or web) | school bag prior to school visit | school bag prior to school visit | school bag prior to school visit | school bag prior to school visit | school bag prior to school visit | Clinical Record From | Interaction analysis |
Secondary | Non-NHS costs | Parent-completed questionnaire: (paper or web) | school bag prior to school visit | school bag prior to school visit | school bag prior to school visit | school bag prior to school visit | school bag prior to school visit | Clinical Record From | |
Secondary | Respiratory infection Health care use NHS costs | Data extraction from GP health records | Gathered after year 4 school visits complete | Gathered after year 4 school visits complete | Gathered after year 4 school visits complete | Gathered after year 4 school visits complete | Gathered after year 4 school visits complete | Clinical Record Form | Interaction analysis |
Secondary | Health care use NHS costs | Data extraction from GP health records, HES+++ data linkage | n/a | n/a | n/a | n/a | Data extraction in year 5 | Clinical Record Form/HES data | Interaction analysis |
Secondary | SARS-CoV-2 antibodies | Finger-prick blood test | n/a | n/a | n/a | School visit | n/a | Clinical Record Form | Interaction analysis |