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Table 2 Diagnostic parameters in comparisons between the BA and non-BA groups in the model design cohort

From: Development and validation of a model for early diagnosis of biliary atresia

Parameter

AUC

p value

Cut-off

Sensitivity

Specificity

PPV

NPV

Accuracy

Clay-like stool

0.651

< 0.01

 

43.5%

86.8%

58.8%

78.0%

73.7%

DBIL (µmol/L)

0.638

0.01

53.5

94.2%

34.4%

43.8%

91.7%

55.4%

DBIL/TBIL (%)

0.671

< 0.01

63.4

80.8%

45.8%

44.7%

81.5%

58.1%

γGT (U/L)

0.787

< 0.01

184.0

76.9%

75.0%

62.5%

85.7%

75.6%

Abnormal gallbladder

0.660

< 0.01

 

91.9%

48.4%

51.5%

90.9%

64.6%

TC sign (mm)

0.754

< 0.01

3.6

63.0%

90.0%

94.4%

94.4%

70.2%

  1. BA Biliary atresia, Non-BA Nonbiliary atresia, AUC Area under the receiver operating characteristic curve, PPV Positive predictive value, NPV Negative predictive value, DBIL Direct bilirubin, TBIL Total bilirubin, γGT Gamma glutamyl transpeptidase, TC sign Triangular cord sign