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Table 1 Clinical, laboratory, and ultrasonographic characteristics of the model design cohort

From: Development and validation of a model for early diagnosis of biliary atresia

Characteristics

BA (n = 52)

Non-BA (n = 96)

P value

Age (days)

48 ± 10

44 ± 11

0.02

Male sex (%)

24(46.2)

53(55.2)

0.31

Clay-like stool (%)

10(43.5)

7(13.2)

< 0.01

ALT(U/L)

173.7 ± 112.2

165.8 ± 155.6

0.78

AST(U/L)

284.2 ± 163.8

244.0 ± 212.8

0.28

TBIL (µmol/L), median (IQR)

165(130,200)

159(80.5,211)

0.06

DBIL (µmol/L), median (IQR)

116(95.5,154)

97(32.5,149.5)

0.01

DBIL/TBIL (%), median (IQR)

74.6(67.7,82.6)

66.9(54.4,78.2)

< 0.01

γGT (U/L), median (IQR)

447(206,822)

165(104,319)

< 0.01

LDH (U/L),median (IQR)

410(322.5,649)

485(336.5,809)

0.15

ALP (U/L)

616.7 ± 248.1

501.6 ± 275.9

0.07

TBA (µmol/L)

157.1 ± 63.0

124.1 ± 70.5

0.17

Hepatomegaly (%)

2(10.5)

5(8.6)

0.80

Abnormal gallbladder (%)

34(91.9)

2(2.8)

< 0.01

TC sign positive (%)

30(81.1)

12(20.7)

< 0.01

  1. BA Biliary atresia, Non-BA Non-biliary atresia, ALT Alanine transaminase, AST Aspartate transaminase, IQR Interquartile range, TBIL Total bilirubin, DBIL Direct bilirubin, γGT Gamma glutamyl transpeptidase, LDH Lactate dehydrogenase, ALP Alkaline phosphatase, TBA Total bile acid, TC Triangular cord, ANOVA Analysis of variance