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Table 2 Comparison of incidence of adverse events between the two groups

From: Safety and efficacy of therapeutic hypothermia in neonates with mild hypoxic-ischemic encephalopathy

Variable

TH group

n = 31

Non-TH group

n = 40

P Value

Hypotension requires vasoactive drug treatment

4 (12.9)

1 (2.5)

0.218

PPHN requires NO treatment and FiO > 0.50

1 (3.2)

0 (0.0)

0.898

Blood transfusions required for coagulation dysfunction

3 (9.7)

0 (0.0)

0.157

Hypoglycemia

7 (22.6)

7 (17.5)

0.594

Stress hyperglycemia

7 (22.6)

3 (7.5)

0.142

Liver insufficiency

5 (16.1)

2 (5.0)

0.247

Renal insufficiency

2 (6.5)

0 (0.0)

0.365

Thrombocytopenia

5 (16.1)

2 (5.0)

0.247

Septicemia

5 (16.1)

4 (10.0)

0.682

  1. Abbreviations: TH Therapeutic hypothermia, PPHN Persistent pulmonary hypertension, NO Nitric oxide, FiO Inhaled oxygen concentration