Table 1 Baseline Maternal and Infant Characteristics between the two groups
From: Safety and efficacy of therapeutic hypothermia in neonates with mild hypoxic-ischemic encephalopathy
Variable | TH group n = 31 | Non-TH group n = 40 | P Value |
|---|---|---|---|
Maternal Characteristics | |||
Age, y, mean ± SD | 28.2 ± 4.2 | 28.3 ± 5.1 | 0.921 |
Complications of pregnancya, n(%) | 4 (12.9) | 6 (15.0) | 0.801 |
Intrapartum complicationsb, n(%) | 22 (71.0) | 21 (52.5) | 0.114 |
Cesarean section, n(%) | 7 (22.6) | 13 (32.5) | 0.357 |
Infant Characteristics | |||
Male, n(%) | 20 (64.5) | 22 (55.0) | 0.418 |
Birth weight, g, mean ± SD | 3307 ± 516.0 | 3227 ± 471.1 | 0.498 |
Gestational age, week, mean ± SD | 39.5 ± 1.2 | 39.3 ± 1.5 | 0.500 |
Apgar score, median(IQR) | |||
1 min | 3 (2–5) | 4 (2.3-5) | 0.733 |
5 min | 6 (5–7) | 7 (5–8) | 0.033 |
Resuscitation at birth, n(%) | |||
Positive pressure ventilation > 10 min | 10 (32.3) | 6 (15.0) | 0.084 |
Tracheal intubation | 21 (67.7) | 16 (40.0) | 0.020 |
Chest compressions > 30 s | 12 (38.7) | 6 (15.0) | 0.023 |
Adrenalin | 7 (22.6) | 5 (12.5) | 0.261 |
Arterial blood gas in umbilical artery or 1 h postnatal, mean ± SD | |||
pH | 7.06 ± 0.14 n = 19 | 7.02 ± 0.08 n = 6 | 0.490 |
BE, mmol/L | -18.7 ± 4.8 n = 19 | -19.3 ± 4.6 n = 6 | 0.804 |
Initial time of Enteral feeding, day, median(IQR) | 4 (3–4) | 1 (1–2) | < 0.001 |
Analgesic and sedative drug use, n(%) | 14 (45.2) | 7 (17.5) | 0.011 |
Age at admission, h, median(IQR) | 4.0 (2.5-5.0) | 3.3 (2.5–6.5) | 0.995 |
Length of stay, day, median(IQR) | 12.5 (11–14) | 9 (7-13.9) | 0.003 |