Signs of the syndrome | Body skin | Mental retardation | Gastrointestinal system | Head and face | Oral | Neck | Extremities and skeletal system |
---|---|---|---|---|---|---|---|
Type of involvements and locations | Multiple popular (on the neck, back, and lumber) Populonodular (body skin) | No | Diarrhea but no specific disease | Multiple rashes (around the nose) Popular firm lesions resembling pearl-shape, keratolytic psoriasis (ear helix) Wide nasal ridge | lower lip protrusion alveolar ridge swelling open mouth Embedded erupted teeth under the gingiva | Plaque–like lesions with non-smooth surface and erythematous base (mostly on posterior site) | Three main palmar lines (absence of other palmar lines) Lumber deformity halluces hypotonic myopathy joint stiffness dysarthria |