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Table 2 Changes in benzodiazepine dispensing to children and youth following the introduction of the OHIP+ pharmacare program in January 2018

From: Impact of a publicly-funded pharmacare program policy on benzodiazepine dispensing among children and youth: a population-based natural experiment

Stratification

Rate of benzodiazepine dispensing (individuals per 100,000)

December 2017

Rate of benzodiazepine dispensing (individuals per 100,000

March 2019

Relative percent change, December 2017 to March 2019 (95% confidence interval

ARIMA Model

January 2018 Step Intervention Estimate (95% confidence interval)

Overall

214.2

241.5

12.8% (9.6 to 16.0%)

(2,1 12,0) no intercept

12.9 (7.5 to 18.3)

Sex

Female

255.5

295.5

15.7% (11.4 to 20.0%)

(2,1 12,0) no intercept

16.5 (8.3 to 24.7

Male

174.9

190.3

8.8% (4.0 to 13.7%)

(3,1 12,0) no intercept

9.3 (5.2 to 13.4)

Age

0 to 9

21.7

24.8

14.7% (-1.6 to 32.3%)

(3,1 12,0) no intercept

1.1 (-0.3 to 2.4)

10 to 14

62.4

67.2

7.6% (-4.9 to 21.0%)

(2,1 12,0) no intercept

-0.56 (-4.8 to 3.6)

15 to 19

303.1

326.2

7.6% (1.9 to 13.9%)

(2,1 12,0) no intercept

16.5 (7.0 to 26.0)

20 to 24

581.6

675.9

16.2% (12.0 to 20.5%)

(2,1 12,0) no intercept

41.1 (26.0 to 56.1)

Income quintile

Quintile 1 (lowest)

223.0

257.6

15.5% (8.4 to 22.9%)

(0,1 12,1) no intercept

14.7 (9.0 to 20.5)

Quintile 2

215.8

258.2

19.6% (11.9 to 27.6%)

(2,1 12,0) no intercept

15.9 (8.4 to 23.4)

Quintile 3

208.8

231.6

10.9% (3.8 to 18.3%)

(3, 1 12,0) no intercept

7.1 (1.7 to 12.5)

Quintile 4

201.1

229.1

13.9% (6.6 to 21.5%)

(2,1 12,0) no intercept

16.5 (7.0 to 26.0)

Quintile 5 (highest)

224.8

236.4

5.2% (-1.3 to 11.8%)

(2,1 12,0) no intercept

14.1 (5.3 to 22.9)

Rural versus urban residence

Rural

212.2

229.6

8.2% (-1.7 to 18.6%)

(0,1 12,3) no intercept

14.6 (4.6 to 24.6)

Urban

215.0

243.4

13.2% (9.9 to 16.7%)

(2,1 12,0) no intercept

12.4 (7.0 to 17.8)