Table 6 Transplantation effect comparison
From: Clinical features, epidemiology, and treatment of Shwachman-Diamond syndrome: a systematic review
Feature | HLA-identical HSCT | HLA-haploidentical umbilical cord blood transplantation | HLA-haploidentical HSCT |
|---|---|---|---|
Case number | 14 | 5 | 3 |
Median age of onset, months | 2.4 | 3.6 | 3.6 |
Median age at diagnosis, years | 0.5 | 1.0 | 4.0 |
Neutropenia [n (%)] | 11(78.6) | 5(100.0) | 3(100.0) |
Three lineages decreased [n (%)] | 6(42.9) | 2(40.0) | 2(66.7) |
Secondary tumor [n (%)] | 7(50.0) | 1(20.0) | 2(66.7) |
Pancreatic diseases [n (%)] | 12(85.7) | 5(100.0) | 2(66.7) |
Short stature [n (%)] | 7(50.0) | 2(40.0) | 1(33.3) |
Skeletal Anomalies[n (%)] | 9(64.3) | 1(20.0) | 2(66.7) |
c.183-184TA > CT &c.258 + 2T > C[n (%)] | 12(85.7) | 5(100.0) | 3(100.0) |
Death[n (%)] | 3(21.4) | 0 | 2(66.7) |
Median age of follow-up time, years | 4 | 1 | 1.6 |