Table 2 Hematological abnormalities in SDS patients
From: Clinical features, epidemiology, and treatment of Shwachman-Diamond syndrome: a systematic review
Hematological abnormality | Proportion %(n/N) |
|---|---|
Peripheral blood routine | 96.8(151/156) |
Pancytopenia | 33.8(51/151) |
Neutropenia | 88.1(133/151) |
Thrombocytopenia | 56.3(85/151) |
Anemia | 51.0(77/151) |
No cytopenia | 4.0(6/151) |
Cytopenia in three lineages | 33.8(51/151) |
Cytopenia in two lineages | 31.8(48/151) |
Cytopenia in one lineage | 30.5(46/151) |
Bone marrow examination | 64.1(100/156) |
malignant lesions | 24.7(20/81) |
AML | 13.6(11/81) |
MDS | 11.1(9/81) |
Aplastic anemia | 32.1(26/81) |