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Table 1 Comparison of clinical characteristics between T1DM and HCs

From: Evaluation of sympathetic skin response for early diagnosis and follow-up of diabetic peripheral neuropathy in children

Variables

HCs

T1DM

Statistic values

P-value

Number

30

85

  

Male/Female, n

14/16

36/49

χ2 = 0.168

0.682

Age,years,median(IQR)

11(8.8 ~ 12.3)

10(8 ~ 12.5)

Z = 0.440

0.660

Body Mass Index,Kg/m2,median(IQR)

16(15.4 ~ 19.9)

15.9(15.1 ~ 19.6)

Z = 0.679

0.497

Glycated hemoglobin, % median(IQR)

5.3(4.7 ~ 5.6)

9.4(8.9 ~ 13.2)

Z = 7.568

< 0.001

Duration of diabetes,years, median(IQR)

 

3(1 ~ 5)

  

SSR (palm)

    

 Onset latency,sec, median(IQR)

1.21(1.15 ~ 1.24)

1.36(1.22 ~ 1.46)

Z = 4.792

< 0.001

 N latency,sec, median(IQR)

1.85(1.78 ~ 1.92)

2.10(1.88 ~ 2.30)

Z = 4.334

< 0.001

 P latency,sec, median(IQR)

2.88(2.73 ~ 2.96)

2.99(2.59 ~ 3.31)

Z = 1.973

0.049

SSR (sole)

    

 Onset latency,sec, median(IQR)

1.69(1.65 ~ 1.77)

1.77(1.61 ~ 1.99)

Z = 2.245

0.025

 N latency,sec, median(IQR)

2.40(2.38 ~ 2.58)

2.58(2.35 ~ 2.92)

Z = 1.659

0.097

 P latency,sec, median(IQR)

3.17(2.93 ~ 3.41)

3.49(3.14 ~ 3.95)

Z = 3.623

< 0.001

Median nerve,median(IQR)

    

 MCV (m/s)

54.5(53.2 ~ 57.0)

54.8(51.5 ~ 57.6)

Z = 0.392

0.695

 CMAP (mV)

7.0(5.8 ~ 9.4)

7.3(5.8 ~ 9.2)

Z = 0.475

0.635

 SCV (m/s)

55.2(52 ~ 56.5)

51.7(49.1 ~ 55.4)

Z = 2.950

0.003

 SNAP (µV)

43.9(29.8 ~ 58.7)

36.5(23.9 ~ 49.7)

Z = 1.551

0.121

Ulnar nerve,median(IQR)

    

 MCV (m/s)

54.9(54.1 ~ 58.1)

54.7(52.8 ~ 57.8)

Z = 0.838

0.402

 CMAP (mV)

5.9(4.4 ~ 6.7)

5.4(4.0 ~ 6.7)

Z = 0.602

0.547

 SCV (m/s)

55.1(53.2 ~ 56.3)

51.5(47.3 ~ 54.2)

Z = 4.243

< 0.001

 SNAP (µV)

22.4(15.9 ~ 35.6)

21.0(14.6 ~ 32.2)

Z = 0.803

0.422

Tibial nerve,median(IQR)

    

 MCV (m/s)

52.5(50.1 ~ 54.3)

46.3(44.7 ~ 48.4)

Z = 7.164

< 0.001

 CMAP (mV)

9.7(8.9 ~ 10.9)

9.2(7.8 ~ 10.8)

Z = 1.564

0.118

Peroneal nerve,median(IQR)

    

 MCV (m/s)

50.5(49.6 ~ 53.5)

47.8(45.1 ~ 50.8)

Z = 3.988

< 0.001

 CMAP (mV)

1.4(0.9 ~ 2.2)

1.3(0.8 ~ 2.0)

Z = 0.673

0.501

Sural nerve,median(IQR)

    

 SCV (m/s)

54.9(53.4 ~ 56.4)

49.0(45.6 ~ 55.6)

Z = 3.405

0.001

 SNAP (µV)

5.7(2.8 ~ 7.8)

4.9(3.0 ~ 7.3)

Z = 0.838

0.402

  1. Note. T1DM = Type 1 diabetes mellitus; HCs = Health controls ; SSR = Sympathetic skin response; MCV = Motor conduction velocity; CMAP = Compound muscle action potential;
  2. SCV = Sensory conduction velocity; SNAP = Sensory nerve action potential; Z = Rank sum test.