Table 1 Participant characteristics according to sepsis development in children with Staphylococcus aureus bloodstream infections
Variables | Total | Sepsis | Non-sepsis | P value |
|---|---|---|---|---|
(n = 94) | (n = 35) | (n = 59) | ||
Boys, n (%) | 59 (62.8) | 20 (57.1) | 39 (66.1) | 0.39 |
Age (months), median (IQR) | 12.0 (0.9–51.0) | 12.0 (2.0–41.5) | 12.0 (0.6–58.0) | 0.38 |
Preterm birth, n (%) | 8 (8.5) | 4 (11.4) | 4 (6.8) | 0.44 |
Prior hospitalization within 6 months, n (%) | 52 (55.3) | 16 (45.7) | 36 (61.0) | 0.15 |
Surgical history within 2 weeks, n (%) | 25 (26.6) | 11 (31.4) | 14 (23.7) | 0.41 |
Hospital-acquired infection, n (%) | 43 (45.7) | 21 (35.6) | 22 (62.9) | 0.01 |
Venous catheter, n (%) | 35 (37.2) | 24 (68.6) | 11 (18.6) | < 0.01 |
MRSA, n (%) | 42 (44.7) | 17 (48.6) | 25 (42.4) | 0.56 |
Underlying diseases n (%) | 46 (48.9) | 28 (60.9) | 18 (39.1) | < 0.01 |
 Congenital heart disease, n (%) | 16 (17.0) | 9 (25.7) | 7 (11.9) |  |
 Gastrointestinal malformation, n (%) | 12 (12.8) | 8 (22.9) | 4 (6.8) |  |
 Tumor, n (%) | 16 (17.0) | 10 (28.6) | 6 (10.2) |  |
 Other, n (%) | 2 (2.1) | 1 (2.9) | 1 (1.7) |  |
Source of bloodstream infection | Â | Â | Â | 0.07 |
 Skin and soft tissue infection, n (%) | 39 (41.5) | 15 (42.9) | 24 (40.7) |  |
 Primary bacteremia, n (%) | 15 (16.0) | 6 (17.1) | 9 (15.3) |  |
 Pneumonia, n (%) | 19 (20.2) | 11 (31.4) | 8 (13.6) |  |
 Osteomyelitis, n (%) | 12 (12.8) | 1 (2.9) | 11 (18.6) |  |
 Other sources, n (%) | 9 (9.6) | 2 (5.7) | 7 (11.9) |  |
Prophylactic antibiotics, n (%) | 59 (62.7) | 24 (68.6) | 35 (59.3) | 0.37 |
Length of hospital stay, days, median (IQR) | 19.0 (9.0–37.5) | 29.0 (13.0–47.0) | 16.0 (8.5–30.0) | < 0.01 |