Table 2 Semi-quantitative classification of pancreatic and thyroid antibodies results
From: Prevalence of markers of beta cell autoimmunity and thyroid disease in children with coeliac disease
Pancreatic antibodies | Seroprevalence | Seronegative | + | ++ | +++ | |
|---|---|---|---|---|---|---|
Anti-GAD | CD n= 93 | 2 (2.1%) | 91 (97.8%) | 1 | 0 | 1 |
HC n= 191 | 3 (1.5%) | 188 (98.5%) | 0 | 3 | 0 | |
Anti-ZnT8 | CD n= 92 | 3 (3.2%) | 89 (96.7%) | 1 | 0 | 2 |
HC n= 190 | 8 (4.2%) | 182 (95.8%) | 6 | 1 | 1 | |
Anti-IA2 | CD n=92 | 1 (1.1%) | 91 (98.9%) | 0 | 0 | 1 |
HC n= 190 | 3 (1.5%) | 187 (98.5%) | 2 | 1 | 0 | |
Anti-Insulin | CD n=92 | 1 (1.1%) | 91 (98.9%) | 0 | 1 | 0 |
HC n=195 | 2 (1%) | 193 (98.9%) | 2 | 0 | 0 | |
All T1DM antibodies | CD n= 369 | 7 (1.9%) | 362 (98.1%) | 2 | 1 | 4 |
HC n=766 | 18 (2.3%) | 748 (97.6%) | 12 | 1 | 1 | |
Thyroid antibodies | Seroprevalence | Seronegative | + | ++ | +++ | |
TRAb | CD n=93 | 2 (2.2%) | 91 (97.8%) | 0 | 1 | 1 |
HC n=199 | 2 (1%) | 197 (99%) | 2 | 0 | 0 | |
Anti-TPO | CD n=93 | 0 (0%) | 103 (99%) | 0 | 0 | 0 |
HC n=198 | 5 (2.5%) | 193 (97.5%) | 3 | 2 | 0 | |
Anti-Tg | CD n= 93 | 4 (4.3%) | 89 (95.7%) | 1 | 3 | 0 |
HC n= 199 | 7 (3.5%) | 192 (96.5%) | 3 | 1 | 3 | |
All thyroid antibodies | CD n=279 | 6 (2.1%) | 273 (97.8%) | 1 | 4 | 1 |
HC n=596 | 14 (2.3%) | 582 (97.7%) | 8 | 3 | 3 | |