Table 1 Patient’s characteristics
From: Prevalence of markers of beta cell autoimmunity and thyroid disease in children with coeliac disease
Patients with coeliac disease | Healthy controls | |||||
|---|---|---|---|---|---|---|
Male (n= 35) | Female (n=60) | Total (n=95) | Male (n=80) | Female (n=119) | Total (n=199) | |
Mean age at diagnosis in years (range) | 7.1 (1.25 – 15.25) | 8.7 (2-17) | 8.1 (1.25-17) | |||
Mean age at enrollment (range) | 8.2 (2.0 16.5) | 8.9 (2-18.25) | 8.9 (1.5 – 18.25) | 9.2 (1.5 – 16.5) | 9.2 (2-19) | 9.2 (1.5 -19) |
Mean z-score for weight (range) | -0.2 (-2.5 – 2.5) | -0.4 (-2.6 – 2.5) | -0.3 (-2.6 – 2.6) | -0.1 (-2.6 – 3) | -0.2 (-3 – 3) | -0.2 (-3 – 3) |
Mean z-score for length (range) | -0.2 (-2.6 – 2.4) | -0.4 (-3.3 – 1.8) | -0.3 (-3.3 – 2.4) | -0.5 (-3.8 – 2.8) | 0.2 (-2.8 – 2.7) | -0.1 (-3.8 – 2.8) |
Leading symptom, why patient was tested for coeliac disease n (%) | ||||||
abdominal pain | 32 (33.7%) | 54 (27%) | ||||
failure to thrive/ growth below genetic centile | 21 (22.1%) | 51 (25.6%) | ||||
constipation | 5 (5.3%) | 42 (21.1%) | ||||
flatulence | 1 (1%) | 2 (1%) | ||||
fatigue | 3 (3.2%) | 2 (1%) | ||||
iron deficiency/anemia | 6 (6.3%) | 6 (3%) | ||||
screening due to pos. family history | 9 (9.4%) | - | ||||
screening due to trisomy 21 | 2 (2.1%) | - | ||||
vomiting | - | 5 (2.5%) | ||||
diarrhea | 6 (6.3%) | 2 (1%) | ||||
others | 10 (10.5%) dysphagia, oral ulcer, nausea, urticaria, low appetite, elevated liver parameters, soft stool, vaginal itchiness | 35 (17.6%) dysphagia, anorexia, gastroesophageal reflux, arthritis, amenorrhea, cystitis, eczema, nausea, elevated liver parameters | ||||