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Table 2 Subgroup analysis for the association between aflatoxin B1 and growth indicators of children

From: A systematic review with meta-analysis of the relation of aflatoxin B1 to growth impairment in infants/children

 

Test of association

Test of heterogeneity

Continuous outcome

Subgroup

Studies

β

95%CI

I2 (%)

P

Height

Overall

4

-0.17

-0.25 to -0.09

19.0

0.29

Prospective cohort

3

-0.21

-0.30 to -0.12

0.0

0.60

Non-cohort

1

-0.10

-0.20 to -0.001

-

-

HPLC

2

-0.20

-0.29 to -0.12

0.0

0.44

ELISA

2

-0.14

-0.31 to 0.03

26.0

0. 24

HAZ

Overall

12

-0.17

-0.30 to -0.03

97.2

 < 0.001

Prospective cohort

8

-0.05

-0.10 to -0.01

58.2

0.01

Non-cohort

4

-0.33

-0.75 to 0.10

99.0

 < 0.001

HPLC

6

-0.02

-0.10 to 0.05

73.3

0.002

ELISA

4

-0.31

-0.70 to 0.08

98.9

 < 0.001

TLC

1

-0.46

-0.69 to -0.22

-

-

IDMS

1

-0.18

-0.32 to -0.04

-

-

Adjusted

11

-0.14

-0.29 to -0.001

97.4

 < 0.001

Not-adjusted

1

-0.46

-0.69 to -0.22

-

-

WAZ

Overall

8

-0.18

-0.33 to -0.02

97.9

 < 0.001

Prospective cohort

5

-0.05

-0.07 to -0.03

4.3

0.38

Non-cohort

3

-0.32

-0.69 to 0.05

96.7

 < 0.001

HPLC

3

-0.06

-0.11 to -0.02

41.1

0.18

ELISA

3

-0.33

-0.78 to 0.12

99.3

 < 0.001

TLC

1

-0.20

-0.48 to 0.08

-

-

IDMS

1

-0.03

-0.17 to 0.11

-

-

Adjusted

7

-0.17

-0.34 to -0.01

98.2

 < 0.001

Not-adjusted

1

-0.20

-0.48 to 0.08

43.2

0.17

WHZ

Overall

6

-0.02

-0.07 to 0.03

43.6

0.11

Prospective cohort

4

-0.01

-0.07 to 0.04

59.6

0.06

Non-cohort

2

-0.07

-0.27 to 0.13

18.7

0.26

HPLC

4

-0.01

-0.05 to 0.03

0.0

0.50

ELISA

1

-0.06

-0.10 to -0.02

-

-

IDMS

1

0.09

-0.04 to 0.22

-

-

Dichotomous outcome

Subgroup

Studies

Odds ratio

95%CI

I2 (%)

P

Stunting

Overall

6

1.15

0.98 to 1.35

80.3

 < 0.001

Prospective cohort

3

1.21

1.11 to 1.33

0.0

0.50

Non-cohort

3

1.14

0.80 to 1.63

43.5

0.15

Underweight

Overall

3

1.08

0.92 to 1.27

70.6

0.03

Prospective cohort

1

1.20

1.03 to 1.40

-

-

Non-cohort

2

0.99

0.98 to 1.00

0.0

0.37

Wasting

Overall

1

1.00

0.98 to 1.02

-

-

  1. WHZ Weight-for-height z score, WAZ Weight-for-age z-score, HAZ Height-for-age z-scores, HPLC High-performance liquid chromatography, ELISA Enzyme-linked immunosorbent assay, TLC Thin layer chromatography, IDMS Isotope dilution mass spectrometry