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Table 2 Time introduced to infant cereal pairwise comparisons at 4 vs. 6 months and eczema and wheezing risk by family history of asthma and breastfeeding duration

From: Timing of introduction to solid food, eczema and wheezing in later childhood: a longitudinal cohort study

Atopic Outcome

Family History of Asthma

No Family History of Asthma

Breast fed < 4mo

(OR (95% CI; P))

n = 287a

Breastfed ≥ 4mo

(OR (95% CI; P))

n = 1466a

Breast fed < 4mo

(OR (95% CI; P))

n = 834a

Breastfed ≥ 4mo

(OR (95% CI; P))

n = 4630a

Eczemab

1.25(0.72,2.18; 0.43)

0.91(0.71,1.14; 0.39)

1.62(1.12,2.35; 0.01)

1.06(0.90,1.25; 0.47)

Wheezeb

0.63(0.37,1.08; 0.10)

0.90(0.72, 1.13; 0.37)

1.29(0.93,1.81; 0.13)

1.31(1.13,1.52; < .001)

  1. a Numbers may not add up to total due to missing values
  2. b Models adjusted for birth weight, child age (RCS, 5 knots), child sex, child season of birth, gestational age, parental ethnicity, family income, household smoking, number of siblings and non-linear time introduced to infant cereal (RCS, 5 knots). Family history of asthma and breastfeeding duration included as effect modifiers. Introduction to infant cereal at 6 months is the reference group