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Table 4 Per protocol analysis of the main and interaction effects of the mFICare intervention components on maternal mental health

From: Maternal mental health after infant discharge: a quasi-experimental clinical trial of family integrated care versus family-centered care for preterm infants in U.S. NICUs

Models and statistics

PTSD (PPQ) models*

Depression (EPDS) models**

Rounds participation

  

1. Main effects

  

 Coefficients (95% CI) [p-value]

  

  a) Rounds participation (ref = low)

0.19 (-0.11, 0.49) [0.22]

0.16 (-0.09, 0.42) [0.20]

  b) Stress at study enrollment (PSS:NICU, score, log)

1.05 (0.56, 1.55) [< 0.001]

0.50 (0.10, 0.90) [0.015]

 Adjusted R2

0.223

0.069

 Model F-statistic {df} [p-value]

8.53 {6,151} [< 0.001]

3.55 {5,166} [0.005]

2. Interaction effect

  

 Coefficients (95% CI) [p-value]

  

  a) Rounds participation (ref = low)

1.02 (0.25, 1.80) [0.010]

0.63 (-0.02, 1.28) [0.12]

  b) Stress at study enrollment (PSS:NICU, score, log)

1.50 (0.88, 2.12) [< 0.001]

0.77 (0.24, 1.30) [0.004]

  c) Interaction of a) and b)

-1.08 (-2.00, -0.16) [0.022]

-0.60 (-1.37, 0.17) [0.12]

 Adjusted R2

0.245

0.077

 Model F-statistic {df} [p-value]

8.28 {7,150} [< 0.001]

3.38 {6,165} [0.004]

Parent class attendance

  

1. Main effects

  

 Coefficients (95% CI) [p-value]

  

  a) Class attendance (ref = no)

0.12 (-0.19, 0.42) [0.46]

0.16 (-0.10, 0.42) [0.22]

  b) Stress at study enrollment (PSS:NICU, score, log)

1.05 (0.56, 1.55) [< 0.001]

0.49 (0.09, 0.89) [0.017]

 Adjusted R2

0.219

0.069

 Model F-statistic {df} [p-value]

8.31 {6,151} [< 0.001]

3.52 {5,166} [0.005]

2. Interaction effect

  

 Coefficients (95% CI) [p-value]

  

  a) Class attendance (ref = no)

0.98 (0.17, 1.78) [0.018]

0.93 (0.26, 1.60) [0.007]

  b) Stress at study enrollment (PSS:NICU, score, log)

1.48 (0.87, 2.10) [< 0.001]

0.87 (0.37, 1.37) [< 0.001]

  c) Interaction of a) and b)

-1.09 (-2.03, -0.15) [0.024]

-0.98 (-1.76, -0.19) [0.015]

 Adjusted R2

0.240

0.096

 Model F-statistic {df} [p-value]

8.07 {7,150} [< 0.001]

4.02 {6,165} [< 0.001]

  1. EPDS = Edinburgh Postnatal Depression Scale; PPQ = Perinatal Post-Traumatic Stress Disorder Questionnaire; PTSD = Post-Traumatic Stress Disorder; PSS:NICU = Parental Stressor Scale: NICU.
  2. * PTSD model adjusted for site, length of hospital stay, 5-minute Apgar score, and mother’s perception of FCC quality at enrollment.
  3. ** Depression model adjusted for NICU site and infant gestational age.
  4. Note: Parent mentorship and We3healthâ„¢ app usage were unrelated to maternal health outcomes (data not shown).