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Table 3 Intent-to-treat analysis of the main and interaction effects of the mFICare intervention on maternal mental health

From: Maternal mental health after infant discharge: a quasi-experimental clinical trial of family integrated care versus family-centered care for preterm infants in U.S. NICUs

Models and statistics

PTSD (PPQ) models*

Depression (EPDS) models**

1. Main effects only

  

 Coefficients (95% CI) [p-value]

  

  a) mFICare (ref = FCC)

0.15 (-0.15, 0.45) [0.33]

0.10 (-0.16, 0.35) [0.45]

  b) Stress (PSS:NICU score) at study enrollment (log)

1.05 (0.55, 1.54) [< 0.001]

0.50 (0.10, 0.90) [0.015]

 Adjusted R2

0.221

0.063

 Model F-statistic {df} [p-value]

8.41 {6,151} [< 0.001]

3.31 {5,166} [0.007]

2. Interaction effect

  

 Coefficients (95% CI) [p-value]

  

  a) mFICare (ref = FCC)

1.07 (0.39, 2.72) [0.007]

0.69 (0.04, 1.33) [0.037]

  b) Stress (PSS:NICU score) at study enrollment (log)

1.55 (0.32, 4.91) [< 0.001]

0.85 (0.32, 1.39) [0.002]

  c) Interaction of a) and b)

-1.18 (-2.10, -0.26) [0.012]

-0.76 (-1.53, 0.006) [0.052]

 Adjusted R2

0.248

0.079

 Model F-statistic {df} [p-value]

8.38 {7,150} [< 0.001]

3.45 {6,165} [0.003]

  1. EPDS = Edinburgh Postnatal Depression Scale; FCC: family-centered care; PPQ = Perinatal Post-Traumatic Stress Disorder Questionnaire; PTSD = Post-Traumatic Stress Disorder; PSS:NICU: Parental Stressor Scale: NICU.
  2. * PTSD model adjusted for site, length of hospital stay, 5-minute Apgar score, and mother’s perception of FCC quality at enrollment.
  3. ** Depression model adjusted for NICU site and infant gestational age.