Fig. 3From: Central nervous system manifestations of LRBA deficiency: case report of two siblings and literature reviewT2-FLAIR hyperintense contrast-enhanced lesions occurring widely spread in the supratentorial (a) and infratentorial (b) grey matter. As in Fig. 2, the arachnoidal cyst in the left temporal region can also be observed (b, dashed arrow). Evolution after 6 months of treatment with abatacept can be seen on the follow-up images depicted with (ii), demonstrating global regression of the lesions and decreased contrast enhancement. Images from patient P1Back to article page