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Table 4 Suspected drugs associated with liver injury in children by anatomical class

From: Liver injury in children: signal analysis of suspected drugs based on the food and drug administration adverse event reporting system

ATC code (1st level)

Anatomical main group

Number of suspected drugs, n (%)

J

Anti-infectives for systemic use

75 (28.4)

L

Antineoplastic and immunomodulating agents

69 (26.1)

N

Nervous system

26 (9.8)

A

Alimentary tract and metabolism

20 (7.6)

C

Cardiovascular system

17 (6.4)

M

Musculo-skeletal system

10 (3.8)

B

Blood and blood-forming organs

8 (3.0)

P

Antiparasitic products, insecticides, and repellents

7 (2.7)

H

Systemic hormonal preparations, excl. sex hormones and insulins

6 (2.3)

V

Various

6 (2.3)

R

Respiratory system

4 (1.5)

D

Dermatologicals

2 (0.8)

G

Genito urinary system and sex hormones

1 (0.4)

NA

No ATC code

13 (4.9)

Total

264 (100)

  1. ATC: anatomic therapeutic chemical