Table 2 Top 10 drugs by number of hepatic injury reports in children

Paracetamol (N02BE01)

1365

3.3

1,968.2

3.6 (3.4–3.8)

Methotrexate (L01BA01)

878

2.4

668.6

2.5 (2.3–2.7)

Vincristine (L01CA02)

649

2.8

728.4

3.0 (2.8–3.3)

Valproic acid (N03AG01)

511

3

661.3

3.2 (2.9–3.6)

Cyclophosphamide (L01AA01)

490

2.3

342

2.4 (2.2–2.6)

Tacrolimus (L04AD02)

427

2.3

310.2

2.4 (2.2–2.7)

Prednisone (H02AB07)

416

2

211.8

2.1 (1.9–2.3)

Prednisolone (H02AB06)

401

2.2

256.3

2.3 (2.1–2.5)

Etoposide (L01CB01)

378

2.2

249.6

2.3 (2.1–2.6)

Cytarabine (L01BC01)

344

2.6

349.4

2.8 (2.5–3.2)