Table 1 Characteristics of hepatic adverse events in children in the period 2004–2020
Characteristics | Total reports, n (%) |
|---|---|
Sex | Â |
 Male | 7018 (49.6) |
 Female | 6385 (45.2) |
 Missing or unknown | 740 (5.2) |
Age (years) | Â |
 0–2 | 2358 (16.7) |
 3–5 | 2048 (14.5) |
 6–18 | 9737 (68.8) |
Country (top five) | Â |
 US | 5073 (35.8) |
 Japan | 1029 (7.3) |
 France | 1013 (7.2) |
 Great Britain | 964 (6.8) |
 Germany | 531 (3.8) |
Outcome | Â |
 Hospitalization | 7207 (37.2) |
 Death | 1878 (9.7) |
 Life-threatening | 1535 (7.9) |
 Disability | 448 (2.3) |
 Congenital anomaly | 227 (1.2) |
 Required intervention | 162 (0.8) |
 Generating injury | 162 (0.8) |
 Other serious or missing outcomes | 7758 (40.0) |