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Table 1 Demographic, clinical, and laboratory characteristics of included newborns and mothers

From: Risk factors associated with vitamin D deficiency in preterm neonates: a single-center step-wise regression analysis

Variable

Total (n = 54)

Vitamin D sufficient newborns (n = 51)

Vitamin D deficient newborns (n = 3)

P-value

(Intergroup differences)

Mean ± SD / Median [ IQR] / Frequency (%)

Mean ± SD / Median [ IQR] / Frequency (%)

Mean ± SD / Median [ IQR] / Frequency (%)

Newborns

Gender

Boy

33 (61.1%)

30

3

0.155

Girl

21 (38.9%)

21

0

Gestational age (weeks)

33 ± 3.4

32.1 ± 2.03

30 ± 2.65

0.16

33 [31–34]

33 [31–33]

29 [28 – ?]

Birth weight (grams)

1836 ± 488.98

1848.7 ± 492.5

1633.3 ± 450.9

0.493

Delivery Route

Cesarean section

40 (74.1%)

38 (74.5%)

2 (66.6%)

0.763

Vaginal (NVD)

14 (25.9%)

13 (25.5%)

1 (33.3%)

Neonatal Serum Vitamin D level (ng/mL)

45.3 ± 19.7

47.23 ± 18.74

14.0 ± 5.29

 < 0.001***

Vitamin D group

Sufficient (≥ 20 ng/mL)

51 (94.44%)

-

-

-

Deficient (< 20 ng/mL)

3 (5.56%)

-

-

Mothers

Maternal age (years)

31.2 ± 2.9

29.61 ± 6.51

30 ± 7.0

0.739

31 [25.5 – 34]

31 [24.5 – 33.5]

33 [22 – ?]

Pregnancy-related adversities

Gestational diabetes

Negative

51 (94.44%)

48 (94.12%)

3 (100%)

0.666

Positive

3 (5.56%)

3 (5.88%)

0 (0%)

Pregnancy-induced hypertension

Negative

49 (90.74%)

47 (92.16%)

2 (66.67%)

0.139

Positive

5 (9.26%)

4 (7.84%)

1 (33.33%)

Taking vitamin D during pregnancy

Negative

26 (48.15%)

24 (47.06%)

2 (66.67%)

0.509

Positive

25 (46.3%)

27 (52.94%)

1 (33.33%)

Receiving antenatal corticosteroids

Negative

24 (44.44%)

23 (45.1%)

1 (33.33%)

0.69

Positive

30 (55.56%)

28 (54.9%)

2 (66.67%)

Maternal Serum Vitamin D level (ng/mL)

28.62 ± 14.08

32.29 ± 14.73

9 ± 1

** < 0.01

Vitamin D group

Sufficient (≥ 20 ng/mL)

43 (79.6%)

43 (84.3%)

0 (0%)

*** < 0.001

Deficient (< 20 ng/mL)

11 (20.4%)

8 (15.7%)

3 (100%)

  1. Abbreviations: SD standard deviation, IQR interquartile range
  2. ? The value could not be measured as only three newborns with vitamin D deficiency
  3. * P-value < 0.05
  4. ** P-value < 0.01
  5. *** P-value < 0.001