Clinical characteristics and antibiotic resistance profile of invasive MRSA infections in newborn inpatients: a retrospective multicenter study from China

Table 4 Antibiotic resistance rates of MRSA from different site of infection

Antibiotics	Soft tissue		Blood stream		Respiratory		Others		χ²	p value
Antibiotics	n	R (%)	n	R (%)	n	R (%)	n	R (%)	χ²	p value
Penicillin	100	100.00	42	100.00	79	100.00	7	100.00	-	-
Erythromycin	99	63.64	42	73.81	74	74.32	7	71.42	2.790	0.425
Clindamycin	99	56.57	42	64.29	74	56.76	7	42.86	1.457	0.692
Levofloxacin	98	3.06	39	15.38	70	8.57	7	0.00	6.580	0.037^*
TMP-SMX	74	2.70	32	9.38	62	4.84	5	0.00	2.950	0.229
Minocycline	34	5.88	7	14.29	27	0.00	2	0.00	0.000	0.439
Gentamicin	99	0.00	42	2.38	77	2.60	7	0.00	-	-
Rifampin	99	0.00	42	0.00	74	0.00	7	0.00	-	-
Vancomycin	100	0.00	42	0.00	79	0.00	7	0.00	-	-
Linezolid	100	0.00	42	0.00	79	0.00	7	0.00	-	-

*, the levofloxacin-resistance rates of blood-derived MRSA strains were significantly higher than that of soft tissue-derived strains (15.38% vs. 3.06%, χ² = 6.903, p = 0.009). Abbreviations: MRSA, methicillin-resistant Staphylococcus aureus; TMP-SMX, sulfamethoxazole-trimethoprim; R, resistant; others, containing bone and joint, central nervous system, hydrothorax, ascites, pericardial fluid, urine

ISSN: 1471-2431