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Table 3 Comparison of the in-hospital nutritional status of infants between the groups

From: Analysis of risk factors for parenteral nutrition-associated cholestasis in preterm infants: a multicenter observational study

 

Non-PNAC (n = 384)

PNAC

(n = 81)

Z/T/χ 2

P

Amino acid dose initiation

(g/kg/day) (mean, IQR)

1.9(1.1,2.1)

1.5(1.,4, 1.9)

-1.935

0.053

Amino acids dose up to 3.0 g/kg/d (days)(mean, IQR)

4.0(3.0,5.0)

4.0(3.0,5.0)

-0.001

1.000

Maximum dose of amino acids (g/kg/day) (mean, IQR)

3.5(3.2,3.7)

4.0(3.5,4.0)

-7.331

<0.001

SMOF (n, %)

202(52.6)

32(39.5)

4.590

0.032

Medium/long-chain fat emulsion (n, %)

182(47.4)

49(60.5)

4.590

0.032

Fat emulsion dose initiation (g/kg/day) (mean, IQR)

1.0(1.0,1.5)

1.0(1.0,1.0)

-0.346

0.729

Fat emulsion dose up to 3.0 g/kg/d (days)(mean, IQR)

5.0(4.0,7.0)

5.0(4.0,7.0)

-1.648

0.099

Maximum dose of fat emulsion (g/kg/day) (mean, IQR)

3.0(3.0,3.0)

3.0(3.0,3.4)

-2.836

0.005

Days of parenteral nutrition (days)(mean, IQR)

25.0(18.0,32.0)

34.0(24.0,43.5)

-5.905

<0.001

Time to initiate enteral feeding (hours) (mean, IQR)

24.0(16.0,41.0)

24.0(18.0,42.8)

-1.793

0.073

Breast feeding (n, %)

209(54.4)

22(27.2)

19.893

<0.001

FI (n, %)

140(36.5)

56(69.1)

29.293

<0.001

Time to reach total enteral nutrition (days)(mean, IQR)

26.0(19.0,34.0)

35.0(24.0,44.8)

-4.169

<0.001

Total calories up to 110 kcal/kg/day (days)(mean, IQR)

12.0(8.0,18.0)

9.5(6.8,16.0)

-2.322

0.020

Days to regain birth weight (days) (mean, IQR)

10.0(8.0,12.0)

10.0(8.0,11.5)

-0.611

0.541

Average velocity of weight growth (g/kg/day) (mean, IQR)

15.2(13.6,17.2)

13.7(12.8,15.5)

-3.322

0.001

  1. PNAC, parenteral nutrition-associated cholestasis; SMOF, soybean oil-medium chain triglycerides-olive oil-fish oil; FI, feeding intolerance