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Table 1 Comparison of clinical information of premature infants in the two groups

From: Analysis of risk factors for parenteral nutrition-associated cholestasis in preterm infants: a multicenter observational study

 

Non-PNAC

(n = 384)

PNAC

(n = 81)

Z/T/χ 2

P

Mean gestational age at birth (weeks, \(\bar {x} \pm s\))

30.1 ± 1.8

29.1 ± 2.2

4.007

<0.001

Mean birth weight (grams, \(\bar {x} \pm s\))

1273.6 ± 248.2

1074.7 ± 279.7

6.406

<0.001

Male (n, %)

198(51.6)

47(58.0)

1.121

0.290

Cesarean section (n, %)

279(72.7)

57(70.4)

0.174

0.676

SGA (n, %)

53(13.8)

17(21.0)

2.701

0.100

Five-minute Apgar scores ≤ 7 (n, %)

37(9.6)

9(11.1)

0.163

0.686

Premature rupture of membranes > 18 h (n, %)

59(15.4)

11(13.6)

0.167

0.683

Invasive mechanical ventilation (days)(mean, IQR)

0.0(0.0,3.0)

3.0(0.0,10.0)

-4.263

<0.001

Non-invasive mechanical ventilation (days)(mean, IQR)

18.0(8.0,31.0)

33.0(15.0,49.8)

-4.220

<0.001

Total duration of oxygen support (days)(mean, IQR)

34.0(18.0,51.0)

52.5(34.8,68.0)

-5.186

<0.001

Maternal gestational diabetes (n, %)

99(25.8)

22(27.2)

0.066

0.797

Maternal hypertension in pregnancy (n, %)

117(30.5)

27(33.3)

0.257

0.612

Total hospital stay (days)(mean, IQR)

47.0(38.0,60.0)

67.0(53.0,82.0)

-6.573

<0.001

  1. PNAC, parenteral nutrition-associated cholestasis; SGA, small for gestational age