Irrational prescription and its costs in neonatal surfactant therapy: public and private hospitals of Iran in 2018

Table 1 Indications of surfactant prescription in neonates

Prescription indications	Indication variables	Status of variables	Define the status of variables
Indication 1	Variable a: Gestational Age	Rational	≥ 37 weeks
	Variable a: Gestational Age	Irrational	< 37 weeks
	Variable b: Progress in the resuscitation operations in the operating / delivery room	Rational	Neonate needs intubation-based resuscitation in the operating/delivery room
		Irrational	Neonate needs no intubation-based resuscitation in the operating /delivery room
Indication 2	Variable a: Gestational Age	Rational	≥ 37 weeks
	Variable a: Gestational Age	Irrational	< 37 weeks
	Variable b: Type of respiratory support before surfactant prescription and Status of the need for the increased CPAP and FIO₂^a	Rational	NCPAP and need to increase CPAP ≥ 8 cm/H₂O or FIO₂ ≥ 30%
		Irrational	Not- NCPAP
Indication 3	Variable a: Gestational Age	Rational	≥ 37 weeks
	Variable a: Gestational Age	Irrational	< 37 weeks
	Variable b: Chest radiography in the first 48 h of birth	Rational	Abnormal
	Variable b: Chest radiography in the first 48 h of birth	Irrational	Normal
Indication 4	Variable a: Type of respiratory distress disease	Rational	RDS or MAS ^bor PNA ^c
	Variable a: Type of respiratory distress disease	Irrational	not-RDS & not-MAS & not-PNA
	Variable b: Progress in the resuscitation operations	Rational	Use of endotracheal intubation
	Variable b: Progress in the resuscitation operations	Irrational	using no endotracheal intubation

ISSN: 1471-2431