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Table 1 Comparison of basic demographic and clinical characteristics between three groups

From: Prevention of human milk-acquired cytomegalovirus infection in very-low-birth-weight infants

Variables

FT

(n = 41)

FT + LP

(n = 42)

FT + HP

(n = 42)

P -value

Gestational age (weeks)

28.32 ± 2.88

27.66 ± 2.91

27.81 ± 2.46

0.82 1

Body weight (g)

1090.85 ± 399.33

1017.90 ± 368.30

1020.83 ± 288.04

0.57 3

Delivery type (NSVD / CS)

9 / 32

13 / 29

7 / 35

0.29 1

Sex (male / female)

19 / 22

20 / 22

24 / 18

0.56 1

Small for gestational age

13 (31.7)

9 (21.4)

11 (26.2)

0.58 3

Surfactant use

31 (75.6)

35 (83.3)

36 (85.7)

0.46 1

Bronchopulmonary dysplasia

21 (51.2)

25 (59.5)

28 (66.7)

0.36 1

Significant patent ductus arteriosus*

18 (43.9)

20 (47.6)

16 (38.1)

0.67 1

Retinopathy of prematurity (≥ stage 2)

7 (17.1)

8 (19.0)

11 (26.2)

0.56 1

Necrotizing enterocolitis

3 (7.3)

5 (11.9)

9 (21.4)

0.16 1

Sepsis

12 (29.3)

17 (40.5)

18 (42.9)

0.40 1

Total parental nutrition days

34.37 ± 23.04

41.31 ± 25.44

47.52 ± 35.31

0.20 4

Days to achieve full enteral feeding

37.66 ± 33.04

43.02 ± 29.67

44.31 ± 31.49

0.30 4

Average HM intake (mL/day)

86.94 ± 62.65

82.15 ± 59.78

75.43 ± 50.04

0.93 4

Proportion of HM in total enteral intake

    

< 25%

4 (9.8)

5 (11.9)

7 (16.7)

0.76 1

25 – 49%

17 (41.5)

12 (28.6)

14 (33.3)

 

50 – 75%

11 (26.8)

11 (26.2)

12 (28.6)

 

> 75%

9 (22.0)

14 (33.3)

9 (21.4)

 

Duration of HM feeding (days)

40.46 ± 17.91

41.29 ± 18.61

42.46 ± 20.03

0.58 4

Numbers of transfusion

    

Packed red blood cell

6.07 ± 8.60

9.33 ± 12.00

6.81 ± 7.61

0.67 4

Platelet concentrate

2.22 ± 4.71

6.38 ± 14.36

2.55 ± 5.49

0.56 4

Fresh frozen plasma

1.10 ± 3.40

2.67 ± 12.30

0.62 ± 1.06

0.67 4

CMV infection

2 (4.9)

4 (9.5)

1 (2.4)

0.40 2

Outcome (survival / death)

40 / 1

39 / 3

41 / 1

0.41 1

  1. Values are either number (%) or mean ± standard deviation
  2. *Defined as conditions needing medical or surgical treatment
  3. 1Chi-squared test, 2Fisher’s exact test, 3ANOVA, 4Kruskal–Wallis test
  4. Abbreviations: FT, freeze-thawing; LP, low-temperature Holder pasteurization; HP, high-temperature short-term pasteurization; NSVD, normal spontaneous vaginal delivery; CS, cesarean section; HM, human milk