From: Prevention of human milk-acquired cytomegalovirus infection in very-low-birth-weight infants
Variables | FT (n = 41) | FT + LP (n = 42) | FT + HP (n = 42) | P -value |
---|---|---|---|---|
Gestational age (weeks) | 28.32 ± 2.88 | 27.66 ± 2.91 | 27.81 ± 2.46 | 0.82 1 |
Body weight (g) | 1090.85 ± 399.33 | 1017.90 ± 368.30 | 1020.83 ± 288.04 | 0.57 3 |
Delivery type (NSVD / CS) | 9 / 32 | 13 / 29 | 7 / 35 | 0.29 1 |
Sex (male / female) | 19 / 22 | 20 / 22 | 24 / 18 | 0.56 1 |
Small for gestational age | 13 (31.7) | 9 (21.4) | 11 (26.2) | 0.58 3 |
Surfactant use | 31 (75.6) | 35 (83.3) | 36 (85.7) | 0.46 1 |
Bronchopulmonary dysplasia | 21 (51.2) | 25 (59.5) | 28 (66.7) | 0.36 1 |
Significant patent ductus arteriosus* | 18 (43.9) | 20 (47.6) | 16 (38.1) | 0.67 1 |
Retinopathy of prematurity (≥ stage 2) | 7 (17.1) | 8 (19.0) | 11 (26.2) | 0.56 1 |
Necrotizing enterocolitis | 3 (7.3) | 5 (11.9) | 9 (21.4) | 0.16 1 |
Sepsis | 12 (29.3) | 17 (40.5) | 18 (42.9) | 0.40 1 |
Total parental nutrition days | 34.37 ± 23.04 | 41.31 ± 25.44 | 47.52 ± 35.31 | 0.20 4 |
Days to achieve full enteral feeding | 37.66 ± 33.04 | 43.02 ± 29.67 | 44.31 ± 31.49 | 0.30 4 |
Average HM intake (mL/day) | 86.94 ± 62.65 | 82.15 ± 59.78 | 75.43 ± 50.04 | 0.93 4 |
Proportion of HM in total enteral intake | Â | Â | Â | Â |
< 25% | 4 (9.8) | 5 (11.9) | 7 (16.7) | 0.76 1 |
25 – 49% | 17 (41.5) | 12 (28.6) | 14 (33.3) |  |
50 – 75% | 11 (26.8) | 11 (26.2) | 12 (28.6) |  |
> 75% | 9 (22.0) | 14 (33.3) | 9 (21.4) |  |
Duration of HM feeding (days) | 40.46 ± 17.91 | 41.29 ± 18.61 | 42.46 ± 20.03 | 0.58 4 |
Numbers of transfusion | Â | Â | Â | Â |
Packed red blood cell | 6.07 ± 8.60 | 9.33 ± 12.00 | 6.81 ± 7.61 | 0.67 4 |
Platelet concentrate | 2.22 ± 4.71 | 6.38 ± 14.36 | 2.55 ± 5.49 | 0.56 4 |
Fresh frozen plasma | 1.10 ± 3.40 | 2.67 ± 12.30 | 0.62 ± 1.06 | 0.67 4 |
CMV infection | 2 (4.9) | 4 (9.5) | 1 (2.4) | 0.40 2 |
Outcome (survival / death) | 40 / 1 | 39 / 3 | 41 / 1 | 0.41 1 |