Table 2 Multivariate analyses associated with clinical outcomes of the 113 patients
From: Outcomes and prognostic factors of infantile acquired hydrocephalus: a single-center experience
Favorable outcome (n = 58) (%) | Adverse outcome (n = 55) (%) | p Value | |
|---|---|---|---|
Male | 36 (62.1) | 39 (70.9) | 0.98 |
Gestational age (wk) | 35.6 ± 3.9 | 35.4 ± 4.4 | 0.79 |
Age at presentation (d) | 23.7 ± 22.8 | 30.0 ± 29.9 | 0.12 |
Etiologies | |||
Post hemorrhage | 32 (55.2) | 22 (40.0) | 0.12 |
Post meningitis | 15 (25.9) | 13 (23.6) | 0.78 |
Both post hemorrhage and post meningitis | 8 (13.8) | 9 (16.4) | 0.70 |
Inherited error of metabolism | 1 (1.7) | 10 (18.2) | |
Tumor/cyst/mass lesions | 2 (3.4) | 1 (1.8) | |
Surgical intervention time (d) a | 12.5 ± 9.9 | 33.7 ± 38.1 | 0.002 |
Ommaya reservoir | 29 (50.0) | 18 (32.7) | |
EVD | 11 (18.9) | 13 (23.6) | |
Subgaleal shunt | 3 (5.1) | 3 (5.5) | |
VPS | 1 (1.7) | 3 (5.5) | |
Intracranial cysto-ventricular shunt | 2 (3.4) | 0 | |
Spontaneous arrest | 12 (20.7) | 6 (10.9) | 0.16 |
Convulsion at onset | 17 (29.3) | 19 (34.5) | 0.36 |
Cerebrospinal fluid | |||
Glucose (mmol/L) | 1.11 ± 0.71 | 1.15 ± 1.05 | 0.82 |
Protein (g/L) | 2.73 ± 2.51 | 2.75 ± 2.43 | 0.97 |
Chloride (mmol/L) | 116.4 ± 6.4 | 115.6 ± 7.2 | 0.54 |
Cranial ultrasonogram | |||
Papile grade (n = 54) b | 32 | 22 | 0.036 |
Grade 3 | 31 (96.9) | 17 (77.3) | |
Grade 4 | 1 (3.1) | 5 (22.7) | |
Left VI (cm) | 2.09 ± 0.54 | 2.49 ± 0.76 | 0.002 |
Right VI (cm) | 1.98 ± 0.49 | 2.42 ± 0.91 | < 0.001 |
Left VH (cm) | 1.73 ± 0.66 | 2.41 ± 1.13 | < 0.001 |
Right VH (cm) | 1.65 ± 0.64 | 2.29 ± 1.17 | < 0.001 |
Left TOD (cm) | 2.79 ± 0.84 | 3.26 ± 0.98 | 0.007 |
Right TOD (cm) | 2.44 ± 0.76 | 2.91 ± 0.95 | 0.001 |
TVW (cm) | 0.90 ± 0.62 | 1.11 ± 0.47 | 0.04 |
Abnormal in aEEG | 18 (31.0) | 23 (41.8) | 0.17 |
Permanent shunt | |||
VP shunt | 18 (31.0) | 20 (36.4) | 0.55 |
Age at VP shunt (mo) | 6.9 ± 3.3 | 5.5 ± 2.5 | 0.14 |