Table 1 Antibiotic resistance patterns of clinical isolates of E.coli from UTI
Antibiotic | Total, n = 120 | O25-B2-ST131, n = 31 | Non- O25-B2-ST131 n = 89 | P-value | |||
|---|---|---|---|---|---|---|---|
S | R | S | R | S | R | ||
Azitromycin | 94(78.3) | 26(21.7) | 28(90.3) | 3(9.7) | 66(74.15) | 23(25.8) | 0.039 |
Ampicillin | 28(23.3) | 92(76.6) | 2(6.4) | 29(93.5) | 26(29.2) | 63(70.8) | 0.013 |
Cefazolin | 42(35) | 78(65) | 4(12.9) | 27(87.1) | 38(42.7) | 51(57.3) | 0.008 |
Cefoxitin | 51(42.5) | 69(57.5) | 9(29) | 22(71) | 42(47.2) | 47(52.8) | 0.029 |
Cefotaxime | 44(37.7) | 76(67.3) | 3(9.7) | 28(90.2) | 41(46) | 48(53.9) | 0.005 |
Ceftazidime | 44(36.7) | 76(63.3) | 7(22.6) | 24(77.4) | 37(41.6) | 52(58.4) | 0.004 |
Cefepime | 49(40.8) | 71(59.2) | 6(19.3) | 25(80.7) | 43(48.3) | 46(51.6) | 0.008 |
Ciprofloxacin | 63(52.5) | 57(57.5) | 10(32.25) | 21(67.7) | 53(59.5) | 36(40.4) | < 0.001 |
Imipenem | 115(95.8) | 5(4.1) | 30(96.7) | 1(3.2) | 85(95.5) | 4(4.4) | 0.764 |
Nalidixic acid | 80(66.6) | 40(33.3) | 21(67.7) | 10(32.2) | 59(66.3) | 30(33.7) | 0.129 |
Gentamicin | 67(55.8) | 53(44.1) | 12(38.7) | 19(61.2) | 55(61.8) | 34(38.1) | 0.175 |
Amikacin | 102(85) | 18(15) | 28(90.3) | 3(9.67) | 74(83.1) | 15(16.7) | 0.661 |
Aztreonam | 64(53.3) | 56(46.6) | 15(48.4) | 16(51.5) | 49(55) | 40(44.9) | 0.001 |
Tetracycline | 35(29.2) | 85(70.7) | 8(25.8) | 23(74.2) | 27(30.3) | 62(69.6) | < 0.001 |
Ampicillin sulbactam | 66(55) | 54(44.9) | 18(58) | 13(41.9) | 48(53.9) | 41(46) | 0.415 |
Amoxicillin-clavulanic acid | 51(42.5) | 69(57.4) | 10(32.2) | 23(67.7) | 41(46) | 48(53.9) | 0.038 |
Piperacillin tazobactam | 73(60.8) | 47(39.1) | 22(71) | 9(29) | 51(57.3) | 38(42.6) | 0.399 |
Meropenem | 114(95) | 6(4.9) | 28(90.3) | 3(9.67) | 86(96.6) | 3(3.3) | 0.679 |
Nitrofurantoin | 90(75) | 30(25) | 26(83.8) | 5(16.1) | 64(71.9) | 25(28) | 0.532 |
Trimethoprim + Sulfamethoxazole | 46(38.3) | 72(61.6) | 9(29) | 22(70.9) | 37(41.5) | 52(58.4) | 0.049 |