| Unadjusted OR (95% CI) | Adjusted OR (95% CI) | |||
---|---|---|---|---|---|
Model 1 | Model 2 | Model 3 | Model 4 | ||
Personal factors | |||||
 Female | 0.64(0.35,1.18) | 0.71 (0.38,1.34) | 0.71(0.37,1.38) | 0.77(0.39,1.52) | 0.99(0.48,2.01) |
 Age (years) | |||||
  6–11 | 1.69(0.90,3.16) | 1.72(0.90,3.28) | 1.63(0.84,3.15) | 1.60(0.80,3.21) | 1.54(0.74,3.21) |
  12–16 | 4.67(1.57,13.89) | 5.02(1.62,15.57) | 4.27(1.32,13.85) | 4.64(1.30,16.50) | 4.98(1.27,19.53) |
 GA (weeks) | |||||
  37–42 | 0.60(0.19,1.85) | 0.42(0.12,1.45) | 0.41(0.11,1.44) | 0.49(0.13,1.93) | 0.42(0.10,1.82) |
   > 42 | 1.12(0.20,6.23) | 1.50(0.26,8.54) | 1.29(0.22,7.67) | 1.78(0.30,10.70) | 1.86(0.26,13.11) |
 BW (g) | |||||
  2500–4000 | 1.32(0.26,6.67) | 1.06(0.19,6.02) | 1.24(0.21,7.26) | 1.08(0.17,6.75) | 1.34(0.20,9.12) |
   > 4000 | 1.15(0.17,7.74) | 0.88(0.12,6.68) | 0.87(0.11,6.91) | 0.66(0.07,6.01) | 0.78(0.08,7.85) |
 Cesarean | 0.93(0.57,1.50) | 0.99(0.59,1.64) | 0.96(0.57,1.62) | 1.04(0.59,1.81) | 1.08(0.60,1.94) |
 Abnormal birth history | 1.99(1.22,3.24) | 2.05(1.21,3.45) | 2.15(1.26,3.67) | 1.95(1.10,3.47) | 1.90(1.03,3.50) |
 With underlying diseases | 1.41(0.87,2.27) | 1.29(0.78,2.13) | 1.27(0.75,2.13) | 1.15(0.66,1.99) | 1.08(0.61,1.91) |
Parental factors | |||||
 Maternal age at pregnancy (years) | |||||
  30–35 | 0.64(0.36,1.14) |  | 0.62(0.34,1.14) | 0.59(0.30,1.18) | 0.51(0.25,1.07) |
   > 35 | 1.41(0.49,4.10) |  | 1.48(0.47,4.68) | 1.46(0.42,5.14) | 1.60(0.41,6.17) |
 Method of feeding (within 6 months after birth) | |||||
  Formula feeding | 1.65(0.95,2.87) |  | 1.58(0.86,2.9) | 1.75(0.91,3.38) | 1.49(0.74,2.99) |
  Mixed feeding | 0.90(0.51,1.60) |  | 0.93(0.50,1.72) | 1.04(0.54,1.99) | 0.84(0.42,1.68) |
 Paternal education level | |||||
  Secondary | 0.62(0.31,1.24) |  | 0.56(0.24,1.32) | 0.60(0.24,1.47) | 0.64(0.24,1.70) |
  University | 0.50(0.29,0.88) |  | 0.43(0.18,1.06) | 0.58(0.22,1.49) | 0.59(0.21,1.63) |
 Maternal education level | |||||
  Secondary | 0.75(0.36,1.53) |  | 1.04(0.43,2.49) | 1.04(0.41,2.61) | 1.06(0.38,2.95) |
  University | 0.65(0.38,1.12) |  | 1.38(0.57,3.34) | 1.09(0.43,2.77) | 1.24(0.46,3.35) |
Family-environmental factors | |||||
 Family structure | |||||
  Stem | 1.26(0.78,2.04) |  |  | 0.97(0.50,1.92) | 0.75(0.36,1.56) |
  Others(non-traditional) | 2.17(0.80,5.91) |  |  | 0.96(0.29,3.14) | 0.74(0.21,2.64) |
 Parenting pattern | |||||
  Slant scold | 3.50(1.72,7.14) |  |  | 2.02(0.84,4.87) | 2.04(0.81,5.11) |
  Slant interference | 1.76(0.91,3.38) |  |  | 1.20(0.58,2.48) | 1.21(0.56,2.60) |
  Indulgence | 3.25(1.69,6.22) |  |  | 2.1(1.01,4.33) | 2.17(1.00,4.69) |
 Parental involvement in care | |||||
  Partially | 1.74(1.03,2.92) |  |  | 2.11(1.04,4.29) | 2.11(1.00,4.48) |
  None | 1.22(0.65,2.28) |  |  | 1.18(0.50,2.76) | 1.08(0.44,2.64) |
 Inharmony family relationship | 2.51(1.39,4.55) |  |  | 1.29(0.60,2.74) | 1.19(0.53,2.67) |
 Family history | |||||
  Parent/close relatives with TD | 2.24(0.79,6.36) |  |  | 1.24(0.37,4.17) | 1.14(0.31,4.18) |
  Parent/close relatives with psychiatric disorders | 6.83(1.77,26.33) |  |  | 7.09(1.59,31.56) | 6.34(1.33,30.30) |
Clinical characteristics | |||||
 CTD/TS | 3.70(2.19,6.26) |  |  |  | 3.45(1.82,6.53) |
 Complex tics | 2.10(1.31,3.34) |  |  |  | 1.21(0.67,2.19) |
 Moderate/Severe tic severity | 3.07(1.89,5.00) |  |  |  | 2.13(1.18,3.84) |