Table 1 Comparison of genotypic and allelic frequencies between cases and controls

rs1017: NG_023040.1:g.16138A > T

ISL1

AA = 0.52

TA = 0.11

TT = 0.37

AA = 0.21

TA = 0.08

TT = 0.71

2.15 × 10–4

T = 0.42

A = 0.58

T = 0.75

A = 0.25

 < 0.0001

rs36208048: NG_008732.1:g.3877C > A

VEGF

CC = 0.68

CA = 0.32

AA = 0.00

CC = 0.67

CA = 0.33

AA = 0.00

0.8921

C = 0.84

A = 0.16

C = 0.84

A = 0.16

0.8577

rs7240256: NG_029226.1:g.23449 T > C

NFATc1

CC = 0.04

CT = 0.78

TT = 0.18

CC = 0.01

CT = 0.44

TT = 0.55

2.11 × 10^–5

T = 0.57

C = 0.43

T = 0.77

C = 0.33

 < 0.0001

rs11067075 NG_007373.1:g.51682G > T

TBX5

GG = 0.21

GT = 0.70

TT = 0.09

GG = 0.56

GT = 0.36

TT = 0.08

1.6 × 10^–4

G = 0.56

T = 0.44

G = 0.74

T = 0.26

2.0 × 10^–4

rs1801133: NG_013351.1:g.14783C > T

MTHFR

CC = 0.25

CT = 0.62

TT = 0.13

CC = 0.88

CT = 0.10

TT = 0.02

2.09 × 10^–9

C = 0.56

T = 0.44

C = 0.93

T = 0.07

 < 0.0001