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Table 1 Age difference analysis of each index

From: Clinical characteristics of 683 children and adolescents, aged 0–18 years, newly diagnosed with type 1 diabetes mellitus in Henan Province: a single-center study

 

0–3 years (n = 236)

4–9 years (n = 229)

10–18 years (n = 218)

P

Sex (male)

139 (58.9%)a

113 (49.3%)b

105 (48.1%)b

0.04*

Onset season

 Spring

49 (20.76%)

50 (21.83%)

55 (25.23%)

0.318

 Summer

54 (22.88%)

65 (28.38%)

50 (22.94%)

 

 Autumn

70 (29.66%)

53 (23.14%)

47 (21.56%)

 

 Winter

63 (26.69%)

61 (26.64%)

66 (30.28%)

 

Family history positivity

48 (20.34%)

41 (17.90%)

41 (18.81%)

0.795

DKA positivity

167 (70.76%)a

134 (58.52%)b

129 (59.17%)b

0.009*

DKA degree

 Mild

64 (38.32%)

64 (47.76%)

60 (46.51%)

0.195

 Moderate and severe

103 (61.68%)

70 (52.24%)

69 (53.49%)

 

Term infant

223 (94.5%)a

194 (84.7%)b

127 (58.3%)c

< 0.001*

Breast milk before 6 months

190 (80.5%)

176 (76.9%)

163 (74.8%)

0.332

HbA1c (%)

11.19 (2.44)a

12.36 (2.47)b

12.24 (3.09)b

< 0.001*

C-peptide (nmol/L)

0.31 (0.14,0.42)a

0.52 (0.24,0.46)b

0.74 (0.28,0.75)b

< 0.001*

Blood glucose (mmol/L)

23.43 (6.61)a

22.94 (7.37)a

20.36 (7.21)b

< 0.001*

25OHD (ng/ml)

20.73 (9.54)a

17.79 (7.19)b

17.08 (6.55)b

< 0.001*

Hospital length of stay (days)

15.88 (6.55)a

14.32 (6.07)b

11.60 (5.45)c

< 0.001*

Disease course (days)

5 (0,15.5)

5 (0,15)

4.5 (0,12)

0.922

Cost (China Yuan)

7481.52 (6166.42,10,495.78)a

6819.28 (5304,8492.66)b

6226.4 (4298.39,8570.15)b

< 0.001*

Polydipsia

206 (87.29%)a

192 (83.84%)a

155 (71.10%)b

0.002*

Polyuria

191 (80.93%)a

179 (78.17%)a

124 (56.88%)b

< 0.001*

Weight loss

56 (23.73%)a

93 (40.61%)b

76 (34.86%)b

< 0.001*

Delayed diagnosis

83 (35.2%)a

50 (21.8%)b

41 (18.8%)b

< 0.001*

ICA positivity

2 (0.8%)a

12 (5.2%)b

14 (6.4%)b

< 0.001*

IAA positivity

42 (17.8%)a

26 (11.3%)b

96 (44%)c

< 0.001*

GADA positivity

140 (59.3%)a

138 (60.2%)a

68 (31.1%)b

< 0.001*

  1. a,b,c means Statistical difference between groups
  2. * means P value< 0.05, statistically significant among the three groups
  3. 25OHD 25-hydroxyvitamin D, HbA1c Hemoglobin A1C, DKA Diabetic ketoacidosis, ICA Islet cell autoantibody, IAA Insulin autoantibody, GADA Glutamic acid decarboxylase antibody