Table 1 Patient demographics and baseline characteristics by age group (ITTI population)
Variable | < 6 years N = 56 | ≥6 to < 12 years N = 81 | Overall N = 137 |
|---|---|---|---|
Age (years) | 2.9 ± 1.7 | 8.5 ± 1.6 | 6.2 ± 3.2 |
 Median | 3.0 | 9.0 | 7.0 |
 Range | 0–5 | 6–11 | 0–11 |
Male, n (%) | 21 (37.5) | 43 (53.1) | 64 (46.7) |
Weight (kg) | 13.53 ± 3.80 | 28.34 ± 7.87 | 22.29 ± 9.78 |
 Median | 14.40 | 26.60 | 20.90 |
 Range | 4.0–21.3 | 16.5–51.0 | 4.0–51.0 |
Body temperature (°C) | 38.84 ± 0.52 | 38.82 ± 0.63 | 38.83 ± 0.58 |
 Median | 38.80 | 38.70 | 38.80 |
 Range | 38.0–40.2 | 38.0–40.5 | 38.0–40.5 |
Sum of two symptom scoresa | 2.6 ± 1.3 | 3.3 ± 1.0 | 3.0 ± 1.2 |
 Median | 3.0 | 3.0 | 3.0 |
 Range | 0–5 | 0–6 | 0–6 |
Time to treatment from influenza onset, n (%) | |||
  ≥ 0 to ≤12 hours | 23 (41.1) | 35 (43.2) | 58 (42.3) |
  > 12 to ≤24 hours | 26 (46.4) | 33 (40.7) | 59 (43.1) |
  > 24 to ≤36 hours | 6 (10.7) | 11 (13.6) | 17 (12.4) |
  > 36 to ≤48 hours | 1 (1.8) | 2 (2.5) | 3 (2.2) |
Influenza virus type (subtype) based on RT-PCR, n (%) | |||
 A(H1N1)pdm09 | 9 (16.1) | 4 (4.9) | 13 (9.5) |
 A(H3N2) | 27 (48.2) | 69 (85.2) | 96 (70.1) |
 B | 16 (28.6) | 4 (4.9) | 20 (14.6) |
 A, subtype not specified | 2 (3.6) | 2 (2.5) | 4 (2.9) |
 Mixed infection | 2 (3.6) | 2 (2.5) | 4 (2.9) |
Influenza vaccinationb, n (%) | 15 (26.8) | 21 (25.9) | 36 (26.3) |
Co-infection with respiratory virus or bacteriac, n (%) | 25 (44.6) | 25 (30.9) | 50 (36.5) |