Table 3 The association between age, sex, Marsh classifications, weight and height, IgA anti-tTG and some of extra-intestinal manifestations and HLA types of children with Celiac disease
| Â | DQ2 | P -value | DQ8 | P -value | DQ6 | P -value | DQ5 | P -value | DQ7 | P -value | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pos N (%) or Mean (SD) | Neg N (%) or Mean (SD) | Â | Pos N (%) or Mean (SD) | Neg N (%) or Mean (SD) | Â | Pos N (%) or Mean (SD) | Neg N (%) or Mean (SD) | Â | Pos N (%) or Mean (SD) | Neg N (%) or Mean (SD) | Â | Pos N (%) or Mean (SD) | Neg N (%) or Mean (SD) | Â | ||
Sex | Â | Â | 1.000 | Â | Â | 0.433 | Â | Â | 0.664 | Â | Â | 0.464 | Â | Â | 0.021 | |
 Male | 22 (31.4) | 4 (5.7) |  | 9 (13.0) | 17 (24.6) |  | 3 (4.5) | 22 (32.8) |  | 8 (11.9) | 17 (25.4) |  | 0 (0.0) | 25 (37.3) |  | |
 Female | 38 (54.3) | 6 (8.6) |  | 19 (27.5) | 24 (34.8) |  | 3 (4.5) | 39 (58.2) |  | 10 (14.9) | 32 (47.8) |  | 9 (13.4) | 33 (49.3) |  | |
Marsh Class | Â | Â | 0.008 | Â | Â | 0.032 | Â | Â | 0.027 | Â | Â | 0.702 | Â | Â | 0.003 | |
 2b | 1 (1.6) | 1 (1.6) |  | 2 (3.2) | 0 (0.0) |  | 0 (0.0) | 2 (3.2) |  | 1 (1.6) | 1 (1.6) |  | 1 (1.6) | 1 (1.6) |  | |
 3a | 23 (35.9) | 2 (3.1) |  | 10 (15.9) | 14 (22.2) |  | 1 (1.6) | 23 (37.1) |  | 8 (12.9) | 16 (25.8) |  | 4 (6.5) | 20 (32.3) |  | |
 3b | 21 (32.8) | 3 (4.7) |  | 9 (14.3) | 15 (23.8) |  | 1 (1.6) | 22 (35.5) |  | 6 (9.7) | 17 (27.4) |  | 2 (3.2) | 21 (33.9) |  | |
 3c | 9 (14.1) | 2 (3.1) |  | 1 (1.6) | 10 (15.9) |  | 4 (6.5) | 7 (11.3) |  | 2 (3.2) | 9 (14.5) |  | 0 (0.0) | 11 (17.7) |  | |
IgA Anti-tTGa | 250.13 (232.34) | 317.49 (310.34) | 0.681 | 293.18 (261.10) | 243.44 (234.71) | 0.588 | 205.62 (168.16) | 268.30 (253.75) | 0.747 | 258.61 (258.89) | 263.92 (244.64) | 0.754 | 185.99 (163.75) | 273.34 (255.55) | 0.423 | |
Age | 8.03 (3.05) | 10.10 (4.07) | 0.063 | 9.50 (3.40) | 7.59 (2.97) | 0.016 | 9.33 (2.07) | 8.31 (3.36) | 0.469 | 8.33 (3.83) | 8.43 (3.08) | 0.917 | 8.11 (2.80) | 8.45 (3.36) | 0.776 | |
Weighta | 26.60 (17.79) | 33.80 (19.99) | 0.100 | 35.97 (25.97) | 22.45 (7.13) | 0.005 | 29.50 (9.59) | 27.56 (19.14) | .196 | 25.64 (15.54) | 28.55 (19.51) | 0.519 | 25.62 (6.93) | 28.08 (19.67) | 0.798 | |
Heighta | 122.45 (21.59) | 132.40 (28.32) | 0.098 | 129.60 (28.46) | 120.38 (17.94) | 0.038 | 130.17 (19.93) | 123.18 (23.39) | 0.383 | 122.22 (23.83) | 124.44 (22.97) | 0.692 | 125.67 (14.52) | 123.53 (24.22) | 0.827 | |
Extra-intestinal manifestations | ||||||||||||||||
Headache | Â | Â | 0.681 | Â | Â | 0.223 | Â | Â | 0.752 | Â | Â | 0.541 | Â | Â | 0.011 | |
 Presence | 1 (1.4) | 0 (0.0) |  | 1 (1.4) | 0 (0.0) |  | 0 (0.0) | 1 (1.5) |  | 0 (0.0) | 1 (1.5) |  | 1 (1.5) | 0 (0.0) |  | |
 Absence | 59 (84.3) | 10 (14.3) |  | 27 (39.1) | 41 (59.4) |  | 6 (9.0) | 60 (89.5) |  | 18 (26.9) | 48 (71.6) |  | 8 (11.9) | 58 (86.6) |  | |
Autoimmune thyroid disease | Â | Â | 0.528 | Â | Â | 0.513 | Â | Â | 0.246 | Â | Â | 0.025 | Â | Â | 0.417 | |
 Presence | 3 (4.3) | 1 (1.4) |  | 1 (1.5) | 3 (4.3) |  | 1 (1.5) | 3 (4.5) |  | 3 (4.5) | 1 (1.5) |  | 0 (0.0) | 4 (6.0) |  | |
 Absence | 56 (81.4) | 9 (12.9) |  | 27 (39.1) | 38 (55.1) |  | 5 (7.5) | 58 (86.5) |  | 15 (22.4) | 48 (71.6) |  | 9 (13.4) | 54 (80.6) |  | |