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Table 1 Clinical and demographic characteristics of patients undergoing sepsis workup in the neonatal intensive care unit, according to bacterial or non-bacterial causes

From: Time from symptom onset may influence C-reactive protein utility in the diagnosis of bacterial infections in the NICU

 

Bacterial (N = 21)

Non bacterial

(N = 108)

P value

Demographic characteristics

 Gestational age, weeks

 Median (IQR)

28 (27,38)

32 (27,36)

0.1

 Gestational weight, grams, Median (IQR)

1800 (1030,3037)

1925 (1125,2641)

0.9

 Preterm (<=36 + 6 week of gestation), N (%)

20 (95%)

87 (80.5%)

0.3

 Age at CRP in days,

 Median (IQR)

10.5 (5,68)

9.5 (2,25)

0.01

Clinical characteristics

   

 Interval between symptoms onset and CRP, hours, median (IQR)

3.5 (1.5,18)

5 (2.7,12)

0.8

 Central Venous catheter,

N (%)

8 (38)

22 (20)

0.09

 Surgery prior to sepsis

 Workup, N(%)

7(33)

11 (10)

0.01

0.8

 Absolute neutrophil count, cells/mm3,Median (IQR)

8.2 (1.9,16.4)

5.9 (2.5,9.3)

0.01

 CRP value, mg/dL

 Median (IQR)

8 (1.3,21)

0.35 (0.3,1.5)

0.0001

  1. *CRP C-reactive protein
  2. IQR Interquartile range