Study | Country | Age | N | Setting | Inclusion criteria | Treatment group | Control group | ||
---|---|---|---|---|---|---|---|---|---|
Name | Interface | Name | Interface | ||||||
Milési et al. (18) | France | 1 d to 6 mon | 142 | PICU | Bronchiolitis, and moderate to severe respiratory distress | HFNC | Optiflow system | CPAP | Infant Flow Ventilator or FlexiTrunk infant interface |
Sarkar et al. (19) | India | 28 d to 1 y | 31 | PICU | Severe bronchiolitis consistent with clinical features, SpO2 < 92% in room air, and RDAI ≥ 11 | HFNC | Nasal prong | CPAP | Nasal prong or nasal mask |
Vahlkvist et al. (20) | Denmark | < 2 y | 50 | ED | Bronchiolitis and need for respiratory support | CPAP | Nasal prong | HFNC | Nasal prong |
Borgi et al. (21) | Tunisia | 7 days to 6 months | 255 | PICU | Clinical diagnosis of bronchiolitis of moderate severity Wang modified score ≥ 10 | CPAP | Nasal mask or nasal prongs | HFNC | Nasal cannula |
Cesar et al. (8) | Brazil | < 9 mon | 63 | PICU | Diagnosis of bronchiolitis of moderate severity or greater | CPAP | Nasal prong | HFNC | Nasal cannula |