Table 1 The fusion break points of YAP1 and MAML2 genes in pediatric meningioma
From: Pediatric meningioma with a Novel MAML2-YAP1 fusion variant: a case report and literature review
Case # | Age | Sex | Tumor location | Gene fusion | Fused exons | WHO grade | Subtypes |
|---|---|---|---|---|---|---|---|
1 | 4 | F | Lateral ventricles, third ventricle | YAP1:MAML2 | Ex5:Ex2 | II* | Atypical* |
2 | 1 | M | Third ventricle, lateral ventricle | YAP1:MAML2 | Ex1:Ex2 | NA | NA |
3 | 2 | M | Skull base | YAP1:MAML2 | Ex1 and 2nd intron:1st intron | NA | NA |
4 | 17 | M | Cavernous sinus | YAP1:MAML2 | Ex5:Ex2 | I* | Transitional |
5 | 7 | F | Parietal | YAP1:MAML2 | Ex5:Ex2 | NA | With focal rhabdoid features |
6 | 7 | F | Frontal | YAP1:MAML2 | Ex5:Ex2 | I | With rhabdoid features |
7△ | 12 | M | Parafalcine | MAML2:YAP1 | Ex1:Ex7 | I | With focal rhabdoid features |