Effect of neonatal reticulocytosis on glucose 6-phosphate dehydrogenase (G6PD) activity and G6PD deficiency detection: a cross-sectional study

Table 7 The prevalence of G6PD deficiency in male and female newborns, assuming different thresholds for deficiency. The prevalence was calculated based on G6PD activity measured by spectrophotometric and automated UV enzymatic assays

Male G6PD deficiency prevalence		Threshold G6PD activity expressed as percent of normal
At 10%		30%			40%			60%			70%			80%
		M	F	T	M	F	T	M	F	T	M	F	T	M	F	T
Domingo GJ. *et al.* (2019)	No. def	500	124	624	500	237	737	517	656	1173	595	968	1563	864	1313	2177
	% Def	80	20	100	68	32	100	44	56	100	38	62	100	40	60	100
	% Pop	10.0	2.5	6.2	10.0	4.7	7.4	10.3	13.1	11.7	11.9	19.4	15.6	17.3	26.3	21.8
*G6PD activity method*	No	502	513	1015	502	513	1015	502	513	1015	502	513	1015	502	513	1015
Spectrophotometric assay (n)	No. def	50	12	62	52	17	69	56	57	113	58	78	136	79	99	178
	% Def	80.6	19.4	100.0	75.4	24.6	100.0	49.6	50.4	100.0	42.6	57.4	100.0	44.4	55.6	100.0
	% Pop	10.0	2.3	6.1	10.4	3.3	6.8	11.2	11.1	11.1	11.6	15.2	13.4	15.7	19.3	17.5
Automated UV enzymatic assay (n)	No. def	52	14	66	52	23	75	61	74	135	75	97	172	99	125	224
	% Def	78.8	21.2	100.0	69.3	30.7	100.0	45.2	54.8	100.0	43.6	56.4	100.0	44.2	55.8	100.0
	% Pop	10.4	2.7	6.5	10.4	4.5	7.4	12.2	14.4	13.3	14.9	18.9	16.9	19.7	24.4	22.1

ISSN: 1471-2431